Articles with "wistar rats" as a keyword



Toxicological Assessment of a Standardized Dry Extract of Zea mays L. (Poaceae) Stigmas During Gestation: Effects on Maternal Parameters and Fetal Outcomes in Wistar Rats

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Published in 2025 at "Birth Defects Research"

DOI: 10.1002/bdr2.2526

Abstract: Corn (Zea mays L., Poaceae) stigmas, popularly known as corn silk, have been traditionally used for their diuretic properties and to treat urinary tract disorders and hypertension. Although several studies have reported beneficial effects, such… read more here.

Keywords: wistar rats; poaceae stigmas; zea mays; mays poaceae ... See more keywords
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Aging affects cognition and hippocampal ultrastructure in male Wistar rats

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Published in 2021 at "Developmental Neurobiology"

DOI: 10.1002/dneu.22839

Abstract: It is now well established that aging is associated with emotional and cognitive changes. Although the basis of such changes is not fully understood, ultrastructural alterations in key brain areas are likely contributing factors. Recently,… read more here.

Keywords: male wistar; wistar rats; age groups; area ... See more keywords

Pregestational fructose‐induced metabolic syndrome in Wistar rats causes sexually dimorphic behavioral changes in their offspring

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Published in 2024 at "Developmental Neurobiology"

DOI: 10.1002/dneu.22940

Abstract: Metabolic syndrome (MetS), marked by enduring metabolic inflammation, has detrimental effects on cognitive performance and brain structure, influencing behavior. This study aimed to investigate whether maternal MetS could negatively impact the neurodevelopment and metabolism of… read more here.

Keywords: pregestational fructose; omets females; wistar rats; fructose induced ... See more keywords

Ameliorative effect of nanoencapsulated flavonoid against chlorpyrifos‐induced hepatic oxidative damage and immunotoxicity in Wistar rats

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Published in 2018 at "Journal of Biochemical and Molecular Toxicology"

DOI: 10.1002/jbt.22050

Abstract: The theme of the present work is to evaluate the protective effect of nanoencapsulated quercetin (NEQ) against chlorpyrifos (CPF)‐induced hepatic damage and immune alterations in animals. Nanoparticles (NP) drug encapsulation was prepared. Forty male Wistar… read more here.

Keywords: oxidative damage; effect nanoencapsulated; damage; wistar rats ... See more keywords

Effect of Rythmol (propafenone HCl) administration during pregnancy in Wistar rats

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Published in 2022 at "Journal of Biochemical and Molecular Toxicology"

DOI: 10.1002/jbt.23085

Abstract: Propafenone is a well‐known Class 1C antiarrhythmic agent that has sodium channel blocking properties as well as the ability to block 13 other channels and a modest calcium antagonistic effect. Propafenone has a profound electrophysiologic… read more here.

Keywords: effect; effect rythmol; rythmol propafenone; propafenone ... See more keywords

Bergapten mediated inflammatory and apoptosis through AMPK/eNOS/AKT signaling pathway of isoproterenol‐induced myocardial infarction in Wistar rats

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Published in 2022 at "Journal of Biochemical and Molecular Toxicology"

DOI: 10.1002/jbt.23143

Abstract: Bergapten (BeG) is explored for its anti‐inflammatory and antioxidant properties. Myocardial infarction (MI) is reported to be one of the leading cardiovascular diseases characterized by mitochondrial dysfunction and apoptosis. The main purpose of this study… read more here.

Keywords: apoptosis; myocardial infarction; beg; wistar rats ... See more keywords

Adverse Effects of Furan on Fetal Development, Growth Plate Integrity, and Placental Functioning in Wistar Rats

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Published in 2025 at "Journal of Biochemical and Molecular Toxicology"

DOI: 10.1002/jbt.70526

Abstract: This study examined the adverse impacts of furan, a pervasive environmental toxin, on fetal development in Wistar rats. Twenty‐eight pregnant rats (seven animals per group) were orally administered different doses of furan (18 and 28 mg/kg),… read more here.

Keywords: fetal development; wistar rats; development; adverse effects ... See more keywords

Effect of prebiotics of Agave salmiana fed to healthy Wistar rats.

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Published in 2017 at "Journal of the science of food and agriculture"

DOI: 10.1002/jsfa.7764

Abstract: BACKGROUND Inulin and other fructans are synthesized and stored in mezcal agave (Agave salmiana). Fructans provide several health benefits and have excellent technological properties, but only few data report their physiological effect when added in… read more here.

Keywords: synbiotic diet; added diet; effect; agave salmiana ... See more keywords

Omega-3-rich Isochrysis sp. biomass enhances brain docosahexaenoic acid levels and improves serum lipid profile and antioxidant status in Wistar rats.

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Published in 2019 at "Journal of the science of food and agriculture"

DOI: 10.1002/jsfa.9884

Abstract: BACKGROUND Isochrysis sp. is a marine microalga rich in eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). The potential use of its biomass as an alternate PUFA source has not been studied in animal models. Male… read more here.

Keywords: docosahexaenoic acid; biomass; isochrysis; wistar rats ... See more keywords

Naringenin (4,5,7‐trihydroxyflavanone) suppresses the development of precancerous lesions via controlling hyperproliferation and inflammation in the colon of Wistar rats

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Published in 2018 at "Environmental Toxicology"

DOI: 10.1002/tox.22528

Abstract: Colon cancer is a world‐wide health problem and one of the most dangerous type of cancer, affecting both men and women. Naringenin (4, 5, 7‐trihydroxyflavanone) is one of the major flavone glycoside present in citrus… read more here.

Keywords: naringenin trihydroxyflavanone; colon wistar; precancerous lesions; inflammation ... See more keywords

Vitamin K protects against 7,12‐dimethylbenz(A)anthracene induced hepatotoxicity in Wistar rats

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Published in 2020 at "Environmental Toxicology"

DOI: 10.1002/tox.23042

Abstract: Humans are daily exposed to 7,12‐dimethylbenz(a)anthracene (DMBA), a well known polycyclic aromatic hydrocarbons (PAH). This study investigated the role of dietary intake of Vitamin K (VK), a polyphenolic compound, with potential antioxidative properties, against DMBA‐induced… read more here.

Keywords: induced hepatotoxicity; dimethylbenz anthracene; dmba; wistar rats ... See more keywords