A systematic review of the clinical use of Withania somnifera (Ashwagandha) to ameliorate cognitive dysfunction
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DOI: 10.1002/ptr.6552
Abstract: Many developed countries are experiencing a rapidly “greying” population, and cognitive decline is common in the elderly. There is no cure for dementia, and pharmacotherapy options to treat cognitive dysfunction provide limited symptomatic improvements. Withania… read more here.
Keywords: withania somnifera; somnifera; systematic review; cognitive dysfunction ... See more keywords
Unveiling the effect of Withania somnifera on neuronal cytoarchitecture and synaptogenesis: A combined in vitro and network pharmacology approach
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DOI: 10.1002/ptr.7466
Abstract: Withania somnifera (WS), is known for its remarkable contribution in herbal medicine and Ayurveda, which is therapeutically applied to improve memory and anxiety in patients. However, the pharmacological details of this plant on memory boosting… read more here.
Keywords: pharmacology; withania somnifera; network; network pharmacology ... See more keywords
Overexpression of WssgtL3.1 gene from Withania somnifera confers salt stress tolerance in Arabidopsis.
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DOI: 10.1007/s00299-021-02666-9
Abstract: KEY MESSAGE Overexpression of Withania somnifera SGT gene (WssgtL3.1) in transgenic Arabidopsis improves various agronomic and physiological traits and alters conjugated sterol levels to mitigate the effect of salt stress. Sterols are essential constituents of… read more here.
Keywords: withania somnifera; overexpression; tolerance; salt stress ... See more keywords
Dietary supplementation with Withania somnifera root powder ameliorates experimentally induced Infectious Bursal Disease in chicken
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DOI: 10.1007/s11250-019-02104-9
Abstract: Infectious Bursal Disease (IBD) is an economically important, immunosuppressive viral disease of chicken. Withania somnifera, a well-known Indian medicinal plant and functional food, finds extensive ethnomedicinal and ethnoveterinary use in the subcontinent. Root extracts of… read more here.
Keywords: withania somnifera; root powder; supplementation; somnifera ... See more keywords
Evaluation of In Vitro Immunomodulatory Activity of Withania somnifera Roots on Human Neutrophils
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DOI: 10.1007/s12010-021-03518-8
Abstract: The present study encompasses in vitro immunomodulatory activity of Withania somnifera WS (Solanaceae) examined on human neutrophils. The isolated compound of Withania somnifera roots was screened for its possible immunomodulatory activity by nitro blue tetrazolium… read more here.
Keywords: immunomodulatory activity; withania somnifera; activity; human neutrophils ... See more keywords
Green Synthesis of Selenium Nanoparticle Using Leaves Extract of Withania somnifera and Its Biological Applications and Photocatalytic Activities
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DOI: 10.1007/s12668-018-0566-8
Abstract: AbstractThe green Se NPs (selenium nanoparticles) are formed by simple mixing of Withania somnifera (W. somnifera) leaves extract and selenious acid (H2SeO3) solution. This mixture was stirred which gave a dispersion of Se NPs conjugated… read more here.
Keywords: withania somnifera; somnifera; leaves extract; analysis ... See more keywords
Withania somnifera as a safer option to hydroxychloroquine in the chemoprophylaxis of COVID-19: Results of interim analysis
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DOI: 10.1016/j.ctim.2021.102768
Abstract: Objectives To study the efficacy and safety of Withania somnifera (WS) in the prophylaxis against COVID-19 in high risk health care workers (HCW) in comparison to hydroxychloroquine (HCQ). To evaluate general physical and mental health… read more here.
Keywords: withania somnifera; hcq; safer option; interim analysis ... See more keywords
Multifunctional neuroprotective effect of Withanone, a compound from Withania somnifera roots in alleviating cognitive dysfunction
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DOI: 10.1016/j.cyto.2017.10.019
Abstract: Graphical abstract Figure. No Caption available. HighlightsWith the increase in life expectancy there is sharp increase in the older patient base raising concerns about the increase in the age related degenerative diseases specifically AD.Since AD… read more here.
Keywords: withania somnifera; bgr; somnifera; compound ... See more keywords
Up-regulation of Squalene synthase in hairy root culture of Withania somnifera (L.) Dunal yields higher quantities of withanolides
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DOI: 10.1016/j.indcrop.2020.112706
Abstract: Abstract The roots of Indian ginseng, Withania somnifera (L.) Dunal (Solanaceae) are extensively used in ayurvedic and other traditional medicines. The plant produces a steroidal lactone, withanolide which has multiple health benefits. Squalene synthase plays… read more here.
Keywords: withania somnifera; squalene synthase; somnifera dunal; synthase ... See more keywords
Withania somnifera (L.) Dunal: A potential therapeutic adjuvant in cancer.
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DOI: 10.1016/j.jep.2020.112759
Abstract: ETHNOPHARMACOLOGICAL RELEVANCE Withania somnifera (L.) Dunal (WS) is one of the most-studied Rasayana botanicals used in Ayurveda practice for its immunomodulatory, anti-aging, adaptogenic, and rejuvenating effects. The botanical is being used for various clinical indications,… read more here.
Keywords: withania somnifera; therapeutic adjuvant; molecular mechanisms; cancer ... See more keywords
Effect of α-amylase inhibitor from Withania somnifera on growth and development of Callosobruchus chinensis and in silico studies on its interactions with insect amylase
Sign Up to like & getrecommendations! Published in 2020 at "Archives of Phytopathology and Plant Protection"
DOI: 10.1080/03235408.2020.1826745
Abstract: Abstract Pulse beetle (Callosobruchus chinensis) is a cosmopolitan stored grain pest of legumes responsible for significant losses in them during storage. A proteinaceous α-amylase inhibitor, isolated and purified from Withania somnifera (WSAI), affected various growth… read more here.
Keywords: withania somnifera; chinensis; amylase; amylase inhibitor ... See more keywords