Comparison of 3 Treatment Strategies for Medication Overuse Headache: A Randomized Clinical Trial.
Sign Up to like & getrecommendations! Published in 2020 at "JAMA neurology"
DOI: 10.1001/jamaneurol.2020.1179
Abstract: Importance Medication overuse headache (MOH) is a disabling, globally prevalent disorder representing a well-known and debated clinical problem. Evidence for the most effective treatment strategy is needed. Objective To compare 3 treatment strategies for MOH.… read more here.
Keywords: preventive group; treatment; medication; withdrawal ... See more keywords
Cannabinoid Type 1 Receptor (CB1) Ligands with Therapeutic Potential for Withdrawal Syndrome in Chemical Dependents of Cannabis sativa
Sign Up to like & getrecommendations! Published in 2017 at "ChemMedChem"
DOI: 10.1002/cmdc.201700129
Abstract: Cannabis sativa withdrawal syndrome is characterized mainly by psychological symptoms. By using computational tools, the aim of this study was to propose drug candidates for treating withdrawal syndrome based on the natural ligands of the… read more here.
Keywords: cannabinoid type; type receptor; withdrawal syndrome; cannabis sativa ... See more keywords
Documentation of patient withdrawals, retention strategies, and postwithdrawal data practices in cancer clinical trials
Sign Up to like & getrecommendations! Published in 2025 at "Cancer"
DOI: 10.1002/cncr.70106
Abstract: The withdrawal of patients from cancer clinical trials with unspecified rationale introduces selection bias, compromises study validity, and reduces generalizability. Excluding these data can lead to informative censoring, masking treatment toxicity, or inflating efficacy estimates.… read more here.
Keywords: cancer; cancer clinical; retention strategies; withdrawal ... See more keywords
Temporal trends in initiation of mineralocorticoid receptor antagonists and risk of subsequent withdrawal in patients with heart failure: A nationwide study in Denmark from 2003-2017.
Sign Up to like & getrecommendations! Published in 2021 at "European journal of heart failure"
DOI: 10.1002/ejhf.2418
Abstract: AIMS Despite landmark heart failure (HF) with reduced ejection fraction (HFrEF) trials showing effect of Mineralocorticoid Receptor Antagonists (MRA) on the risk of death and HF hospitalization, it has been suggested that MRAs are underutilized… read more here.
Keywords: mineralocorticoid receptor; receptor antagonists; heart failure; withdrawal ... See more keywords
Antiseizure medication withdrawal risk estimation and recommendations: A survey of American Academy of Neurology and EpiCARE members
Sign Up to like & getrecommendations! Published in 2022 at "Epilepsia Open"
DOI: 10.1002/epi4.12696
Abstract: Choosing candidates for antiseizure medication (ASM) withdrawal in well‐controlled epilepsy is challenging. We evaluated (a) the correlation between neurologists' seizure risk estimation (“clinician predictions”) vs calculated predictions, (b) how viewing calculated predictions influenced recommendations, and… read more here.
Keywords: neurology; antiseizure medication; withdrawal; risk estimation ... See more keywords
Astrocyte‐selective STAT3 knockdown rescues methamphetamine withdrawal‐disrupted spatial memory in mice via restoring the astrocytic capacity of glutamate clearance in dCA1
Sign Up to like & getrecommendations! Published in 2021 at "Glia"
DOI: 10.1002/glia.24046
Abstract: Methamphetamine (METH) is a common abused drug. METH‐triggered glutamate (Glu) levels in dorsal CA1 (dCA1) could partially explain the etiology of METH‐caused abnormal memory, but the synaptic mechanism remains unclear. Here, we found that METH… read more here.
Keywords: capacity; glu; clearance; withdrawal ... See more keywords
Infant withdrawal and behavior problems in urban Chinese toddlers: Roles of maternal sensitivity to infant distress and emerging delay ability.
Sign Up to like & getrecommendations! Published in 2019 at "Infant mental health journal"
DOI: 10.1002/imhj.21763
Abstract: Using a longitudinal design, this study examined the associations between infant temperamental withdrawal and behavior problems during toddlerhood and tested the moderating effects of maternal sensitivity to infant distress (MSID) and toddlers' ability to delay… read more here.
Keywords: withdrawal; ability; withdrawal behavior; distress ... See more keywords
The structural effects of Vitamin A deficiency on biological macromolecules due to ethanol consumption and withdrawal: An FTIR study with chemometrics
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Biophotonics"
DOI: 10.1002/jbio.202100377
Abstract: The structural effects of vitamin A‐deficiency were examined on the molecular profiles of biomolecules of male rat hippocampus during prolonged ethanol intake/withdrawal using FT‐IR spectroscopy coupled with chemometrics. Liquid ethanol diet with/without vitamin A was… read more here.
Keywords: effects vitamin; ethanol consumption; withdrawal; vitamin deficiency ... See more keywords
Role of noradrenergic transmission within the ventral bed nucleus of the stria terminalis in nicotine withdrawal‐induced aversive behavior
Sign Up to like & getrecommendations! Published in 2022 at "Neuropsychopharmacology Reports"
DOI: 10.1002/npr2.12252
Abstract: Cessation of smoking induces nicotine withdrawal symptoms such as anxiety, depression, and dysphoria, which could lead to smoking relapse. In the present study, we examined the role of noradrenergic transmission within the ventral bed nucleus… read more here.
Keywords: nicotine withdrawal; within ventral; withdrawal; noradrenergic transmission ... See more keywords
Biotin Mitigates Alcohol Withdrawal‐Induced Anxiety and Depression by Regulating Serotonin Metabolism, BDNF, Inflammation, and Oxidative Stress in Rats
Sign Up to like & getrecommendations! Published in 2025 at "Neuropsychopharmacology Reports"
DOI: 10.1002/npr2.12523
Abstract: Substance use disorders, particularly alcohol use disorders, represent a significant public health problem, with adolescents particularly vulnerable to their adverse effects. This study examined the possible anxiolytic and antidepressant effects of biotin, a crucial vitamin… read more here.
Keywords: withdrawal induced; withdrawal; alcohol withdrawal; biotin mitigates ... See more keywords
Efficacy and safety of Sophora alopecuroides var. alopecuroides seed extract for opioid detoxification: A randomized, double‐blind, and placebo‐controlled clinical trial
Sign Up to like & getrecommendations! Published in 2019 at "Phytotherapy Research"
DOI: 10.1002/ptr.6578
Abstract: The seeds of Sophora alopecuroides L. var. alopecuroides (S. alopecuroides) have alleviated morphine withdrawal in mice. Therefore, in this study, the alkaloid composition of S. alopecuroides extract was determined by gas chromatography (GC) and gas… read more here.
Keywords: seed; var alopecuroides; sophora alopecuroides; blood ... See more keywords