Inhibitory Influence of Agmatine in Ethanol Withdrawal-Induced Depression in Rats: Behavioral and Neurochemical Evidences.
Sign Up to like & getrecommendations! Published in 2019 at "Alcohol"
DOI: 10.1016/j.alcohol.2019.09.002
Abstract: Although ethanol withdrawal depression is one of the prominent reasons for its reinstatement and dependence, its neurochemical basis is not clearly understood. Present study investigated the role of agmatinergic system in ethanol withdrawal-induced depression using… read more here.
Keywords: ethanol withdrawal; withdrawal induced; withdrawal; rat ... See more keywords
Stimulation of dorsal hippocampal histaminergic transmission mitigates the expression of ethanol withdrawal-induced despair in mice.
Sign Up to like & getrecommendations! Published in 2021 at "Alcohol"
DOI: 10.1016/j.alcohol.2021.06.002
Abstract: Garnered literature points towards the role of the dorsal hippocampus (CA1) in ethanol withdrawal-induced responses, wherein a strong presence of the histaminergic system is also reported. Therefore, the present study investigated the effect of an… read more here.
Keywords: withdrawal; induced despair; withdrawal induced; ethanol withdrawal ... See more keywords
The Mammalian Circadian Clock Exhibits Chronic Ethanol Tolerance and WithdrawalâInduced Glutamate Hypersensitivity, Accompanied by Changes in Glutamate and TrkB Receptor Proteins
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DOI: 10.1111/acer.13554
Abstract: BACKGROUND Alcohol tolerance and withdrawal-induced effects are criteria for alcohol use disorders listed by the DSM-V. Although tolerance and withdrawal have been studied over many decades, there is still uncertainty regarding mechanistic distinctions that characterize… read more here.
Keywords: tolerance; withdrawal induced; glutamate hypersensitivity; withdrawal ... See more keywords
Inhibition of the Sodium Calcium Exchanger Suppresses Alcohol Withdrawal-Induced Seizure Susceptibility
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DOI: 10.3390/brainsci11020279
Abstract: Calcium influx plays important roles in the pathophysiology of seizures, including acoustically evoked alcohol withdrawal-induced seizures (AWSs). One Ca2+ influx route of interest is the Na+/Ca2+ exchanger (NCX) that, when operating in its reverse mode… read more here.
Keywords: seizure; alcohol withdrawal; susceptibility; withdrawal induced ... See more keywords