Cannabinoid Type 1 Receptor (CB1) Ligands with Therapeutic Potential for Withdrawal Syndrome in Chemical Dependents of Cannabis sativa
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DOI: 10.1002/cmdc.201700129
Abstract: Cannabis sativa withdrawal syndrome is characterized mainly by psychological symptoms. By using computational tools, the aim of this study was to propose drug candidates for treating withdrawal syndrome based on the natural ligands of the… read more here.
Keywords: cannabinoid type; type receptor; withdrawal syndrome; cannabis sativa ... See more keywords
Exploration of potential role of Rho GTPase in nicotine dependence-induced withdrawal syndrome in mice
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DOI: 10.1007/s11356-021-17059-4
Abstract: The RhoA gene showed an important genotypic association with nicotine dependence and smoking initiation. The current study aims to investigate the effect of the Rho GTPase inhibitor ML141 in the progression of nicotine dependence in… read more here.
Keywords: rho gtpase; nicotine dependence; gtpase; withdrawal syndrome ... See more keywords
Level of discomfort in critically ill paediatric patients and its correlation with sociodemographic and clinical variables, analgosedation and withdrawal syndrome. COSAIP multicentre study (Phase 2).
Sign Up to like & getrecommendations! Published in 2021 at "Anales de pediatria"
DOI: 10.1016/j.anpede.2020.10.012
Abstract: INTRODUCTION There are clinical and sociodemographic factors that have an impact on the comfort of the critically ill paediatric patient. The main aim of this study was to determine the level of discomfort of paediatric… read more here.
Keywords: withdrawal syndrome; analgosedation; ill paediatric; discomfort ... See more keywords
[Level of discomfort in critically ill paediatric patients and its correlation with sociodemographic and clinical variables, analgosedation and withdrawal syndrome. COSAIP multicentre study (Phase 2)].
Sign Up to like & getrecommendations! Published in 2020 at "Anales de pediatria"
DOI: 10.1016/j.anpedi.2020.10.016
Abstract: INTRODUCTION There are clinical and sociodemographic factors that have an impact on the comfort of the critically ill paediatric patient. The main aim of this study was to determine the level of discomfort of paediatric… read more here.
Keywords: withdrawal syndrome; analgosedation; ill paediatric; discomfort ... See more keywords
[Ropivacaine withdrawal syndrome: a case report].
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DOI: 10.1016/j.bjan.2019.12.006
Abstract: INTRODUCTION AND OBJECTIVES Ropivacaine is a long-acting local anesthetic that causes prolonged anesthesia and is beneficial for a wide variety of surgeries. Systemic toxicity has been reported after usage of high dose ropivacaine or inadvertent… read more here.
Keywords: ropivacaine; withdrawal syndrome; ropivacaine withdrawal; case report ... See more keywords
Efficiency of Cocarnit preparation in clinical course of alcohol dependence at withdrawal syndrome stage
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DOI: 10.1016/j.eurpsy.2017.02.454
Abstract: Introduction Recently scientific attention of Ukrainian narcology was focused on the group of new complex pharmacological preparations with polymodal pathogenic effect option (Cocarnit, World Medicine, Great Britain). Aims and objectives To ground feasibility of Cocarnit… read more here.
Keywords: withdrawal syndrome; treatment; cocarnit; day ... See more keywords
A subtype-specific neuropeptide FF receptor antagonist attenuates morphine and nicotine withdrawal syndrome in the rat
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DOI: 10.1016/j.neulet.2018.06.053
Abstract: Considerable evidence suggests the Neuropeptide FF (NPFF) and related peptides exert pro-nociceptive and anti-opiate actions, particularly at the supra-spinal level, which may contribute to opiate dependence. The FF1 receptor subtype appears to be primarily responsible… read more here.
Keywords: receptor antagonist; withdrawal syndrome; dependence; ff1 receptor ... See more keywords
Maternal opioid use disorder: Placental transcriptome analysis for neonatal opioid withdrawal syndrome.
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DOI: 10.1016/j.ygeno.2021.08.001
Abstract: Excessive prenatal opioid exposure may lead to the development of Neonatal Opioid Withdrawal Syndrome (NOWS). RNA-seq was done on 64 formalin-fixed paraffin-embedded placental tissue samples from 32 mothers with opioid use disorder, with newborns with… read more here.
Keywords: opioid withdrawal; withdrawal syndrome; opioid use; neonatal opioid ... See more keywords
Neonatal withdrawal syndrome following in utero exposure to antidepressants: a disproportionality analysis of VigiBase, the WHO spontaneous reporting database.
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DOI: 10.1017/s0033291722002859
Abstract: BACKGROUND Evidence on neonatal withdrawal syndrome following antidepressant intrauterine exposure is limited, particularly for antidepressants other than selective serotonin reuptake inhibitor (SSRIs). METHODS In our case/non-case pharmacovigilance study, based on VigiBase®, the WHO database of… read more here.
Keywords: withdrawal syndrome; neonatal withdrawal; syndrome following; disproportionality ... See more keywords
Neonatal opioid withdrawal syndrome: a review of the science and a look toward the use of buprenorphine for affected infants
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DOI: 10.1038/s41372-021-01206-3
Abstract: Neonates born to mothers taking opioids during pregnancy are at risk for neonatal opioid withdrawal syndrome (NOWS), for which there is no recognized standard approach to care. Nonpharmacologic treatment is typically used as a first-line… read more here.
Keywords: opioid withdrawal; withdrawal syndrome; use buprenorphine; neonatal opioid ... See more keywords
Is it time to replace morphine with methadone for the treatment of pain in the neonatal intensive care unit?
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DOI: 10.1038/s41390-021-01472-z
Abstract: The current prescription opioid epidemic in the USA has also resulted in a growing number of pregnant women and their fetuses being exposed to these opioids. For decades it is known that in utero exposure… read more here.
Keywords: opioid withdrawal; withdrawal syndrome; term; treatment ... See more keywords