Predictive Value of C-Reactive Protein and Albumin for Temporal Within-Individual Pharmacokinetic Variability of Voriconazole in Pediatric Hematopoietic Cell Transplant Patients.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of clinical pharmacology"
DOI: 10.1002/jcph.2024
Abstract: Voriconazole is a widely used antifungal agent in immunocompromised patients, but its utility is limited by its variable exposure and narrow therapeutic index. Population pharmacokinetic (PK) models have been used to characterize voriconazole PK and… read more here.
Keywords: voriconazole; variability; temporal within; reactive protein ... See more keywords
Within- and between-individual (co)variance partitioning reveals limited pleiotropic effects of testosterone on immune function, sexual signaling, and parental investment
Sign Up to like & getrecommendations! Published in 2017 at "Behavioral Ecology and Sociobiology"
DOI: 10.1007/s00265-017-2308-2
Abstract: How and why individuals differ from each other is a central question in behavioral and evolutionary ecology, because selection particularly acts on this among-individual variation. It is therefore important to accurately partition phenotypic variances into… read more here.
Keywords: ecology; pleiotropic effects; sexual signaling; within individual ... See more keywords
To be so bold: boldness is repeatable and related to within individual behavioural variability in North Island robins
Sign Up to like & getrecommendations! Published in 2017 at "Behavioural Processes"
DOI: 10.1016/j.beproc.2017.04.014
Abstract: Behavioural research traditionally focusses on the mean responses of a group of individuals rather than variation in behaviour around the mean or among individuals. However, examining the variation in behaviour among and within individuals may… read more here.
Keywords: boldness; variation behaviour; variability; behaviour ... See more keywords
A new year, a new you? Within-individual variation in food purchases
Sign Up to like & getrecommendations! Published in 2020 at "European Economic Review"
DOI: 10.1016/j.euroecorev.2020.103478
Abstract: Abstract We document that within-individual variation in food choices is substantial and has potentially important consequences for nutrition, and hence well-being. We develop an approach that allows us to study the determinants of this within-individual… read more here.
Keywords: individual variation; new year; variation food; within individual ... See more keywords
Somatic mutations ---Evolution within the individual.
Sign Up to like & getrecommendations! Published in 2019 at "Methods"
DOI: 10.1016/j.ymeth.2019.11.002
Abstract: With the rapid advancement of sequencing technologies over the last two decades, it is becoming feasible to detect rare variants from somatic tissue samples. Studying such somatic mutations can provide deep insights into various senescence-related… read more here.
Keywords: evolution; somatic mutations; mutations evolution; within individual ... See more keywords
Directly Mapping Photoelectrochemical Behavior within Individual Transition Metal Dichalcogenide Nanosheets.
Sign Up to like & getrecommendations! Published in 2019 at "Nano letters"
DOI: 10.1021/acs.nanolett.9b02336
Abstract: Spatial variations in photoelectrochemical reaction rates within individual p-type WSe2 nanosheets were mapped through the application of Scanning Electrochemical Cell Microscopy (SECCM). The simultaneous topographical and electrochemical information provided via SECCM directly revealed how both… read more here.
Keywords: metal dichalcogenide; directly mapping; within individual; mapping photoelectrochemical ... See more keywords
Striping modulations and strain gradients within individual particles of a cathode material upon lithiation
Sign Up to like & getrecommendations! Published in 2018 at "Materials horizons"
DOI: 10.1039/c8mh00037a
Abstract: The insertion of Li-ions within cathode materials during the discharging of a battery oftentimes brings about one or more structural transformations. The spatiodynamic propagation of phase transformations within a matrix of particles is determined by… read more here.
Keywords: individual nanowires; within individual; microscopy; cathode materials ... See more keywords
Darwinian selection within an individual or somatic selection: facts and models
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Molecular Cell Biology"
DOI: 10.1093/jmcb/mjz014
Abstract: There are known cases where a cell subpopulation bearing a selective advantage tends to or eventually replaces another cell subpopulation within an organism. This process is supposed to underlie the purging of the most frequent… read more here.
Keywords: darwinian selection; selection within; somatic selection; selection ... See more keywords
Detecting bacterial adaptation within individual microbiomes
Sign Up to like & getrecommendations! Published in 2022 at "Philosophical Transactions of the Royal Society B: Biological Sciences"
DOI: 10.1098/rstb.2021.0243
Abstract: The human microbiome harbours a large capacity for within-person adaptive mutations. Commensal bacterial strains can stably colonize a person for decades, and billions of mutations are generated daily within each person's microbiome. Adaptive mutations emerging… read more here.
Keywords: within individual; individual microbiomes; adaptation within; bacterial adaptation ... See more keywords
Multiple mutations within individual oncogenes
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Science"
DOI: 10.1111/cas.14699
Abstract: Recent studies of the cancer genome have identified numerous patients harboring multiple mutations (MM) within individual oncogenes. These MM (de novo MM) in cis synergistically activate the mutated oncogene and promote tumorigenesis, indicating a positive… read more here.
Keywords: mutations within; evolution; multiple mutations; cancer ... See more keywords
Within-individual repeatability in telomere length: a meta-analysis in non-mammalian vertebrates.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular ecology"
DOI: 10.1111/mec.16155
Abstract: Telomere length is increasingly used as a biomarker of long-term somatic state and future survival prospects. While most studies have overlooked this aspect, biological interpretations based on a given telomere length will benefit from considering… read more here.
Keywords: individual repeatability; repeatability telomere; repeatability; telomere length ... See more keywords