Abstract A033: KRAS codon 12 oncogenic mutations modulate protein conformation within the Switch II/Helix3 pocket
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DOI: 10.1158/1557-3125.ras23-a033
Abstract: Up to 30% of cancers harbor activating mutations in one of three RAS genes, HRAS, NRAS, or KRAS, that drive uncontrolled cellular proliferation, alter cellular metabolism, movement, differentiation, and promote cell survival and tumor immune… read more here.
Keywords: kras g12c; kras g12d; conformation; within switch ... See more keywords