Immune cells within the tumor microenvironment: biological functions and roles in cancer immunotherapy.
Sign Up to like & getrecommendations! Published in 2019 at "Cancer letters"
DOI: 10.1016/j.canlet.2019.11.009
Abstract: The immune cells within the tumor microenvironment (TME) play important roles in tumorigenesis. It has been known that these tumor associated immune cells may possess tumor-antagonizing or tumor-promoting functions. Although the tumor-antagonizing immune cells within… read more here.
Keywords: cells within; within tumor; cancer; immune cells ... See more keywords
Therapeutic Strategies Toward Lactate Dehydrogenase Within the Tumor Microenvironment of Pancreatic Cancer.
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DOI: 10.1097/mpa.0000000000001689
Abstract: OBJECTIVES Pancreatic stellate cells (PSCs) play a key metabolic role within the tumor microenvironment (stroma) of pancreatic ductal adenocarcinoma (PDAC), being glycolytic and associated with protumorigenic acidification from excess lactate. This study investigates the clinical… read more here.
Keywords: lactate dehydrogenase; within tumor; tumor microenvironment; tumor ... See more keywords
Increased Liquefactive Necrosis Formation After Transarterial Chemoembolization Combined with Molecular Targeted Agents Plus Immune Checkpoint Inhibitors for Hepatocellular Carcinoma
Sign Up to like & getrecommendations! Published in 2021 at "Cancer Management and Research"
DOI: 10.2147/cmar.s328812
Abstract: Purpose In clinical practice, we found some of the patients who received transarterial chemoembolization (TACE) with molecular targeted agents (MTGs) plus immune checkpoint inhibitors (ICIs) for hepatocellular carcinoma (HCC) had obvious liquefactive necrosis formation within… read more here.
Keywords: necrosis; within tumor; necrosis formation; liquefactive necrosis ... See more keywords
Clinical and Biological Significance of PD-L1 Expression Within the Tumor Microenvironment of Oral Squamous Cell Carcinoma
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DOI: 10.21873/anticanres.13437
Abstract: Background/Aim: Programmed death-ligand 1 (PD-L1) expression in tumor cells is regulated by a close interrelation between tumor and stromal cells within the tumor microenvironment. Our aim was to evaluate the clinical and biological significance of… read more here.
Keywords: tumor microenvironment; clinical biological; expression; within tumor ... See more keywords
In-Depth Characterization of Stromal Cells within the Tumor Microenvironment Yields Novel Therapeutic Targets
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DOI: 10.3390/cancers13061466
Abstract: Simple Summary This up-to-date and in-depth review describes fibroblast-derived cells and their role within the tumor microenvironment for tumor progression. Moreover, targets for future antitumor therapies are summarized and potential aspects for future translational research… read more here.
Keywords: tumor progression; cells within; stromal cells; within tumor ... See more keywords