Microbiome harbored within tumors: a new chance to revisit our understanding of cancer pathogenesis and treatment
Sign Up to like & getrecommendations! Published in 2020 at "Signal Transduction and Targeted Therapy"
DOI: 10.1038/s41392-020-00244-1
Abstract: In a recent study in Science, Nejmen et al. provide the first comprehensive characterization of the tumor microbiome. Their data reveal that the microbiome mostly resides intracellularly in both tumor and immune cells, and that… read more here.
Keywords: tumor microbiome; treatment; within tumors; microbiome ... See more keywords
Intratumor DNA methylation heterogeneity in glioblastoma: implications for DNA methylation-based classification
Sign Up to like & getrecommendations! Published in 2019 at "Neuro-Oncology"
DOI: 10.1093/neuonc/noz011
Abstract: Abstract Background A feature of glioblastoma (GBM) is cellular and molecular heterogeneity, both within and between tumors. This variability causes a risk for sampling bias and potential tumor escape from future targeted therapy. Heterogeneous intratumor… read more here.
Keywords: methylation; heterogeneity; within tumors; intratumor ... See more keywords