Heparanase and the hallmarks of cancer
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Translational Medicine"
DOI: 10.1186/s12967-020-02624-1
Abstract: Heparanase is the only mammalian enzyme that cleaves heparan sulphate, an important component of the extracellular matrix. This leads to the remodelling of the extracellular matrix, whilst liberating growth factors and cytokines bound to heparan… read more here.
Keywords: heparanase; within tumour; cancer; tumour microenvironment ... See more keywords
Empowering macrophages: the cancer fighters within the tumour microenvironment in mantle cell lymphoma
Sign Up to like & getrecommendations! Published in 2024 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2024.1373269
Abstract: In Mantle Cell Lymphoma (MCL), the role of macrophages within the tumour microenvironment (TME) has recently gained attention due to their impact on prognosis and response to therapy. Despite their low absolute number in MCL… read more here.
Keywords: cell lymphoma; tumour microenvironment; microenvironment; mantle cell ... See more keywords