Pitolisant: A Review in Narcolepsy with or without Cataplexy
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DOI: 10.1007/s40263-020-00703-x
Abstract: Pitolisant (Wakix ® ), an orally available, first-in-class antagonist/inverse agonist of the histamine 3 receptor, is approved in the EU (as of March 2016) for the treatment of narcolepsy with or without cataplexy in adults… read more here.
Keywords: without cataplexy; pitolisant; treatment; narcolepsy without ... See more keywords
Data-Driven Phenotyping of Central Disorders of Hypersomnolence With Unsupervised Clustering
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DOI: 10.1212/wnl.0000000000200519
Abstract: Background and Objectives Recent studies fueled doubts as to whether all currently defined central disorders of hypersomnolence are stable entities, especially narcolepsy type 2 and idiopathic hypersomnia. New reliable biomarkers are needed, and the question… read more here.
Keywords: without cataplexy; data driven; disorders hypersomnolence; central disorders ... See more keywords
Type 1 narcolepsy without cataplexy and treatment progress: a case report.
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DOI: 10.21037/apm-21-220
Abstract: Narcolepsy is a sleep disorder with the main manifestations of excessive daytime sleepiness, cataplexy, sleep paralysis, sleep hallucinations, and nighttime sleep disturbance. It is still not fully recognized by clinicians, and many patients are often… read more here.
Keywords: without cataplexy; narcolepsy without; case; report ... See more keywords