Identification of de novo variants in nonsyndromic cleft lip with/without cleft palate patients with low polygenic risk scores
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Genetics & Genomic Medicine"
DOI: 10.1002/mgg3.2109
Abstract: Nonsyndromic cleft lip with/without cleft palate (nsCL/P) is a congenital malformation of multifactorial etiology. Research has identified >40 genome‐wide significant risk loci, which explain less than 40% of nsCL/P heritability. Studies show that some of… read more here.
Keywords: cleft palate; nonsyndromic cleft; cleft lip; without cleft ... See more keywords
Genetic polymorphism of nonsyndromic cleft lip with or without cleft palate is associated with developmental dyslexia in Chinese school-aged populations
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Human Genetics"
DOI: 10.1038/jhg.2016.121
Abstract: Developmental dyslexia (DD) is a neurodevelopment disorder characterized by reading disabilities without apparent etiologies. Nonsyndromic cleft lip with or without cleft palate (NSCL/P) is a structural craniofacial malformation featured by isolated orofacial abnormalities. Despite substantial… read more here.
Keywords: developmental dyslexia; lip without; nonsyndromic cleft; without cleft ... See more keywords
Association of Axis Inhibition Protein 2 Polymorphisms with Non-Syndromic Cleft Lip with or without Cleft Palate in Iranian Children
Sign Up to like & getrecommendations! Published in 2019 at "Fetal and Pediatric Pathology"
DOI: 10.1080/15513815.2019.1636430
Abstract: Abstract Background: Previously, only a few studies have investigated the association of AXIN2 polymorphisms with nonsyndromic cleft lip with or without cleft palate (NSCLP) risk. Objective: The aim of this study was to examine the… read more here.
Keywords: lip without; iranian children; without cleft; association ... See more keywords
Copy number variation analysis of twin pairs discordant for cleft lip with or without cleft palate
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Immunopathology and Pharmacology"
DOI: 10.1177/2058738419855873
Abstract: Non-syndromic cleft lip with or without cleft palate (nsCL/P) is a frequent orofacial malformation. The comparison of concordance rate observed in monozygotic and dizygotic twins supports high level of heritability and a strong genetic component.… read more here.
Keywords: lip without; cleft palate; without cleft; number ... See more keywords