Activation of formyl peptide receptor 1 elicits therapeutic effects against collagen‐induced arthritis
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DOI: 10.1111/jcmm.16854
Abstract: Rheumatoid arthritis (RA) is an autoimmune disorder which shows production of autoantibodies, inflammation, bone erosion, swelling and pain in joints. In this study, we examined the effects of an immune‐modulating peptide, WKYMVm, that is an… read more here.
Keywords: induced arthritis; wkymvm; th1 th17; collagen induced ... See more keywords
Therapeutic potential of WKYMVm in diseases
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.986963
Abstract: The synthetic hexapeptide WKYMVm, screened from a synthetic peptide library, has been identified as an agonist of FPRs with the strongest activating effect on FPR2. WKYMVm plays an anti-inflammatory role in most inflammatory diseases by… read more here.
Keywords: potential wkymvm; wkymvm diseases; therapeutic potential; wkymvm ... See more keywords
Activation of formyl peptide receptor 2 by WKYMVm enhances emergency granulopoiesis through phospholipase C activity
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DOI: 10.5483/bmbrep.2018.51.8.080
Abstract: Emergency granulopoiesis is a very important strategy to supply efficient neutrophil number in response to infection. However, molecular mechanism involved in this process remains unclear. Here, we found that administration of WKYMVm, an immune modulating… read more here.
Keywords: emergency; wkymvm; emergency granulopoiesis; peptide receptor ... See more keywords