Choroid Plexus Enlargement Exacerbates White Matter Hyperintensity Growth through Glymphatic Impairment.
Sign Up to like & getrecommendations! Published in 2023 at "Annals of neurology"
DOI: 10.1002/ana.26648
Abstract: OBJECTIVE Choroid plexus (CP) is a key regulator in cerebrospinal fluid production, but its contribution to glymphatic clearance function and association with white matter hyperintensity (WMH) remains unclear. METHODS This retrospective study included two prospective… read more here.
Keywords: growth; glymphatic clearance; volume; cohort ... See more keywords
Sex disparity of cerebral white matter hyperintensity in the hypertensive elderly: The Shanghai Changfeng study
Sign Up to like & getrecommendations! Published in 2022 at "Human Brain Mapping"
DOI: 10.1002/hbm.26196
Abstract: White matter hyperintensity (WMH) is associated with vascular hemodynamic alterations and reflects white matter injury. To date, the sex difference of tract‐specific WMH and the relationship between high blood pressure (BP) and tract‐specific WMH remain… read more here.
Keywords: white matter; matter hyperintensity; wmh; wmh index ... See more keywords
White Matter Hyperintensities and Blood Pressure Lowering in Acute Intracerebral Hemorrhage: A Secondary Analysis of the ATACH-2 Trial
Sign Up to like & getrecommendations! Published in 2019 at "Neurocritical Care"
DOI: 10.1007/s12028-019-00761-0
Abstract: Background It is not clear whether subsets of patients with intracerebral hemorrhage (ICH) benefit from intensive blood pressure (BP) lowering. We evaluated whether white matter hyperintensities (WMH) burden influences response to this therapy. Methods Retrospective… read more here.
Keywords: wmh; intracerebral hemorrhage; analysis; blood pressure ... See more keywords
Prospective association of white matter hyperintensity volume and frailty in older adults
Sign Up to like & getrecommendations! Published in 2019 at "Experimental Gerontology"
DOI: 10.1016/j.exger.2019.01.007
Abstract: Background: Frailty is a prevalent geriatric condition and its association with brain health is still weakly investigated. The objective of this study was to examine whether brain white matter hyperintensities (WMH) were related to longitudinal… read more here.
Keywords: wmh; volume; frailty; older adults ... See more keywords
Severity of White Matter Hyperintensities and Effects on All‐Cause Mortality in the Mayo Clinic Florida Familial Cerebrovascular Diseases Registry
Sign Up to like & getrecommendations! Published in 2019 at "Mayo Clinic Proceedings"
DOI: 10.1016/j.mayocp.2018.10.024
Abstract: Objective: To compare all‐cause mortality rates across the severity range of white matter hyperintensities (WMH). Patients and Methods: Between October 26, 2010, and October 5, 2017, the ongoing Mayo Clinic Florida Familial Cerebrovascular Diseases Registry… read more here.
Keywords: wmh; mayo clinic; cause mortality; mortality ... See more keywords
Impact of age and apolipoprotein E ε4 status on regional white matter hyperintensity volume and cognition in healthy aging
Sign Up to like & getrecommendations! Published in 2024 at "Journal of the International Neuropsychological Society"
DOI: 10.1017/s1355617724000122
Abstract: Abstract Objective: White matter hyperintensity (WMH) volume is a neuroimaging marker of lesion load related to small vessel disease that has been associated with cognitive aging and Alzheimer’s disease (AD) risk. Method: The present study… read more here.
Keywords: age; wmh; left temporal; temporal wmh ... See more keywords
White matter hyperintensity shape and location feature analysis on brain MRI; proof of principle study in patients with diabetes
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-20084-y
Abstract: Cerebral small vessel disease is a heterogeneous disease in which various underlying etiologies can lead to different types of white matter hyperintensities (WMH). WMH shape features might aid in distinguishing these different types. In this… read more here.
Keywords: wmh; shape; study patients; principle study ... See more keywords
White matter hyperintensity in different migraine subtypes
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-90341-0
Abstract: The diagnostic value of white matter hyperintensities (WMH) in different types of migraineare unknown. To evaluate the WMH pattern of different subtypes in migraine patients with no vascular risk factors. 92 migraine patients (73 females,… read more here.
Keywords: migraine subtypes; migraine; wmh; different migraine ... See more keywords
Neuropsychiatric systemic lupus erythematosus is associated with a distinct type and shape of cerebral white matter hyperintensities.
Sign Up to like & getrecommendations! Published in 2021 at "Rheumatology"
DOI: 10.1093/rheumatology/keab823
Abstract: OBJECTIVES Advanced white matter hyperintensity (WMH) markers on brain MRI may help reveal underlying mechanisms and aid in the diagnosis of different phenotypes of systemic lupus erythematosus (SLE) patients experiencing neuropsychiatric (NP) manifestations. METHODS In… read more here.
Keywords: wmh; volume; shape; age ... See more keywords
Association of sleep behaviors with white matter hyperintensities and microstructural injury: a cross-sectional and longitudinal analysis of 26,354 participants.
Sign Up to like & getrecommendations! Published in 2023 at "Sleep"
DOI: 10.1093/sleep/zsad020
Abstract: STUDY OBJECTIVES This study assessed the associations between sleep behaviors with white matter macro and microstructure. METHODS A total of 26354 participants in the UK Biobank (mean [standard deviation], age, 63.7 [7.5] years, 53.4% female)… read more here.
Keywords: white matter; sleep behaviors; wmh; behaviors white ... See more keywords
Progression of Cerebral White Matter Hyperintensities and the Associated Sonographic Index.
Sign Up to like & getrecommendations! Published in 2017 at "Radiology"
DOI: 10.1148/radiol.2017162064
Abstract: Purpose To evaluate the relationship between penetrating arterial pulsation and the progression of white matter hyperintensities (WMHs) by using the sonographic resistance index (RI) along the M1 segment of the middle cerebral artery (MCA). Materials… read more here.
Keywords: wmh; index; wmh volume; progression ... See more keywords