A structural MRI study of cholinergic pathways and cognition in multiple sclerosis
Sign Up to like & getrecommendations! Published in 2017 at "eNeurologicalSci"
DOI: 10.1016/j.ensci.2017.06.008
Abstract: Background White matter hyperintensities (WMH) in the cholinergic pathways are associated with cognitive performance in Alzheimer's disease. This study aimed to evaluate the relationship between the volume reduction of cholinergic pathways and cognitive function in… read more here.
Keywords: cholinergic pathways; volume; study; multiple sclerosis ... See more keywords
Cerebral small vessel disease genomics and its implications across the lifespan
Sign Up to like & getrecommendations! Published in 2020 at "Nature Communications"
DOI: 10.1038/s41467-020-19111-2
Abstract: White matter hyperintensities (WMH) are the most common brain-imaging feature of cerebral small vessel disease (SVD), hypertension being the main known risk factor. Here, we identify 27 genome-wide loci for WMH-volume in a cohort of… read more here.
Keywords: small vessel; cerebral small; wmh volume; vessel disease ... See more keywords
Kidney Dysfunction Impact on White Matter Hyperintensity Volume in Neurologically Healthy Adults
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-45109-y
Abstract: The detrimental outcomes of white matter hyperintensity (WMH) are known to be proportional to WMH volume. This study aimed to evaluate the association between kidney dysfunction and white matter hyperintensity (WMH) volume. A total of… read more here.
Keywords: volume; wmh volume; kidney dysfunction; white matter ... See more keywords
Progression of Cerebral White Matter Hyperintensities and the Associated Sonographic Index.
Sign Up to like & getrecommendations! Published in 2017 at "Radiology"
DOI: 10.1148/radiol.2017162064
Abstract: Purpose To evaluate the relationship between penetrating arterial pulsation and the progression of white matter hyperintensities (WMHs) by using the sonographic resistance index (RI) along the M1 segment of the middle cerebral artery (MCA). Materials… read more here.
Keywords: wmh; index; wmh volume; progression ... See more keywords
Abstract WMP59: White Matter Hyperintensities Play a Pivotal Role in Progression of Cerebral Small Vessel Disease: A 7-Year Chinese Urban Community Study
Sign Up to like & getrecommendations! Published in 2020 at "Stroke"
DOI: 10.1161/str.51.suppl_1.wmp59
Abstract: Objective: To explore the role of WMH in progression of CSVD in an urban community in China over a period of 7 years, and to investigate associations between WMH volume (baseline & progression) and cognitive… read more here.
Keywords: progression; role; urban community; wmh volume ... See more keywords
Sample size considerations for trials using cerebral white matter hyperintensity progression as an intermediate outcome at 1 year after mild stroke: results of a prospective cohort study
Sign Up to like & getrecommendations! Published in 2017 at "Trials"
DOI: 10.1186/s13063-017-1825-7
Abstract: BackgroundWhite matter hyperintensities (WMHs) are commonly seen on in brain imaging and are associated with stroke and cognitive decline. Therefore, they may provide a relevant intermediate outcome in clinical trials. WMH can be measured as… read more here.
Keywords: volume; year; intermediate outcome; size ... See more keywords
Longitudinal Changes of White Matter Hyperintensities in Sporadic Small Vessel Disease
Sign Up to like & getrecommendations! Published in 2022 at "Neurology"
DOI: 10.1212/wnl.0000000000201205
Abstract: Background and Objectives White matter hyperintensities (WMHs) are frequent imaging features of small vessel disease (SVD) and related to poor clinical outcomes. WMH progression over time is well described, but regression was also noted recently,… read more here.
Keywords: time; white matter; wmh volume; volume ... See more keywords
Cross-sectional Associations of β-Amyloid, Tau, and Cerebrovascular Biomarkers With Neurodegeneration in Probable Dementia With Lewy Bodies
Sign Up to like & getrecommendations! Published in 2022 at "Neurology"
DOI: 10.1212/wnl.0000000000201579
Abstract: Background and Objectives Although alpha-synuclein–related pathology is the hallmark of dementia with Lewy bodies (DLB), cerebrovascular and Alzheimer disease pathologies are common in patients with DLB. Little is known about the contribution of these pathologies… read more here.
Keywords: dementia lewy; wmh volume; volume; pathology ... See more keywords
Characteristics and Clinical Implication of White Matter Lesions in Patients With Adult Moyamoya Disease
Sign Up to like & getrecommendations! Published in 2023 at "Neurology"
DOI: 10.1212/wnl.0000000000207130
Abstract: Background and Objectives White matter hyperintensities (WMHs) are reportedly increased in moyamoya disease (MMD); however, their clinical importance is not well-established owing to their pathophysiologic heterogeneity by distribution. This study aimed to evaluate the burden… read more here.
Keywords: 001 periventricular; white matter; wmh volume; wmh ... See more keywords
Frontal White Matter Hyperintensities Effect on Default Mode Network Connectivity in Acute Mild Traumatic Brain Injury
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Aging Neuroscience"
DOI: 10.3389/fnagi.2021.793491
Abstract: The functional connectivity of the brain depends not only on the structural integrity of the cortex but also on the white matter pathways between cortical areas. White matter hyperintensities (WMH), caused by chronic hypoperfusion in… read more here.
Keywords: white matter; connectivity; wmh volume; volume ... See more keywords
Value of white matter hyperintensity volume and total white matter volume for evaluating cognitive impairment in patients with cerebral small-vessel disease
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Aging Neuroscience"
DOI: 10.3389/fnagi.2023.1096808
Abstract: Background White matter hyperintensities (WMH) are a key imaging feature of cerebral small-vessel disease (CSVD). However, there is a lack of standardized methods for determining WMH volume, and the value of total white matter (WM)… read more here.
Keywords: white matter; cognitive dysfunction; wmh volume; volume ... See more keywords