The WNK signaling pathway and salt-sensitive hypertension
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DOI: 10.1038/s41440-020-0437-x
Abstract: The distal nephron of the kidney has a central role in sodium and fluid homeostasis, and disruption of this homeostasis due to mutations of with-no-lysine kinase 1 (WNK1), WNK4, Kelch-like 3 (KLHL3), or Cullin 3… read more here.
Keywords: sensitive hypertension; wnk signaling; signaling pathway; salt sensitive ... See more keywords
Glycogen synthase kinase 3ß functions as a positive effector in the WNK signaling pathway
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DOI: 10.1371/journal.pone.0193204
Abstract: The with no lysine (WNK) protein kinase family is conserved among many species. Some mutations in human WNK gene are associated with pseudohypoaldosteronism type II, a form of hypertension, and hereditary sensory and autonomic neuropathy… read more here.
Keywords: glycogen synthase; wnk signaling; signaling pathway; synthase kinase ... See more keywords