Articles with "wnk1" as a keyword



Silencing of long noncoding RNA LEF1‐AS1 prevents the progression of hepatocellular carcinoma via the crosstalk with microRNA‐136‐5p/WNK1

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Published in 2020 at "Journal of Cellular Physiology"

DOI: 10.1002/jcp.29503

Abstract: Long noncoding RNAs (lncRNAs) have been recognized as cancer‐associated biological molecules, favoring hepatocellular carcinoma (HCC) progression. This study was conducted to elucidate the effects lncRNA lymphoid enhancer‐binding Factor 1 antisense RNA (LEF1‐AS1) on the pathological… read more here.

Keywords: hcc; wnk1; lncrna lef1; lef1 as1 ... See more keywords
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WNK1 phosphorylation sites in TBC1D1 and TBC1D4 modulate cell surface expression of GLUT1.

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Published in 2019 at "Archives of biochemistry and biophysics"

DOI: 10.1016/j.abb.2019.108223

Abstract: Glucose uptake by mammalian cells is a key mechanism to maintain cell and tissue homeostasis and relies mostly on plasma membrane-localized glucose transporter proteins (GLUTs). Two main cellular mechanisms regulate GLUT proteins in the cell:… read more here.

Keywords: surface; tbc1d4; expression; glut1 ... See more keywords
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The Nogo receptor inhibits proliferation, migration and axonal extension by transcriptionally regulating WNK1 in PC12 cells

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Published in 2017 at "NeuroReport"

DOI: 10.1097/wnr.0000000000000800

Abstract: Neuronal regeneration and axonal regrowth mechanisms in the injured mammalian central nervous system are largely unknown. As part of a major pathway for inhibiting axonal regeneration, activated neuronal glycosylphosphatidylinositol-anchored Nogo receptor (NgR) interacts with LINGO-1… read more here.

Keywords: proliferation migration; axonal extension; migration axonal; wnk1 ... See more keywords

The C-terminus of WNK1 kinase is evolutionarily conserved and mediates unique phase behavior

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Published in 2023 at "Physiology"

DOI: 10.1152/physiol.2023.38.s1.5735165

Abstract: With-no-lysine 1 (WNK1) is a serine-threonine kinase with two isoforms, long (L)-WNK1 and kidney-specific (KS)-WNK1. L-WNK1 is an ancient kinase that is activated by hypertonic stress. Alternatively, KS-WNK1 emerged more recently, it is only expressed… read more here.

Keywords: ctd; wnk1; physiology; phase ... See more keywords