The WNT Antagonist SFRP1 - a Key Regulator of Periodontal Mineral Homeostasis.
Sign Up to like & getrecommendations! Published in 2019 at "Stem cells and development"
DOI: 10.1089/scd.2019.0124
Abstract: The function of mammalian periodontal tissues depends on the presence of a non-mineralized periodontal ligament juxtaposed in between mineralized tooth anchorage tissues alveolar bone and root cementum. In the present study we have hypothesized that… read more here.
Keywords: wnt antagonist; antagonist sfrp1; mineral homeostasis; alveolar bone ... See more keywords
Hypermethylation of multiple Wnt antagonist genes in gastric neoplasia
Sign Up to like & getrecommendations! Published in 2018 at "Medicine"
DOI: 10.1097/md.0000000000013734
Abstract: Abstract Wnt antagonist genes hypermethylation has been found in several tumors. Accordingly, the events that occur during the progression of adenoma to carcinoma have been characterized and include activation of the Wnt-pathway. Further, gastric adenoma… read more here.
Keywords: wnt antagonist; bgr catenin; hypermethylation; antagonist genes ... See more keywords
Early Determination of the Periodontal Domain by the Wnt-Antagonist Frzb/Sfrp3
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2017.00936
Abstract: Odontogenesis results from the continuous and reciprocal interaction between cells of the oral epithelium and cranial neural crest-derived mesenchyme. The canonical Wnt signaling pathway plays a fundamental role in mediating these interactions from the earliest… read more here.
Keywords: wnt antagonist; frzb; antagonist frzb; frzb sfrp3 ... See more keywords
Identification of a Novel Wnt Antagonist Based Therapeutic and Diagnostic Target for Alzheimer’s Disease Using a Stem Cell-Derived Model
Sign Up to like & getrecommendations! Published in 2023 at "Bioengineering"
DOI: 10.3390/bioengineering10020192
Abstract: Currently, all the existing treatments for Alzheimer’s disease (AD) fail to stall progression due to longer duration of time between onset of the symptoms and diagnosis of the disease, raising the necessity of effective diagnostics… read more here.
Keywords: cell; wnt antagonist; disease; alzheimer disease ... See more keywords