Neonatal Wnt-dependent Lgr5 positive stem cells are essential for uterine gland development
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DOI: 10.1038/s41467-019-13363-3
Abstract: Wnt signaling is critical for directing epithelial gland development within the uterine lining to ensure successful gestation in adults. Wnt-dependent, Lgr5-expressing stem/progenitor cells are essential for the development of glandular epithelia in the intestine and… read more here.
Keywords: uterine gland; wnt dependent; gland development; stem ... See more keywords
Temporal dynamics of Wnt-dependent transcriptome reveal an oncogenic Wnt/MYC/ribosome axis
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Investigation"
DOI: 10.1172/jci122383
Abstract: Activating mutations in the Wnt pathway drive a variety of cancers, but the specific targets and pathways activated by Wnt ligands are not fully understood. To bridge this knowledge gap, we performed a comprehensive time-course… read more here.
Keywords: wnt; dynamics wnt; wnt dependent; dependent transcriptome ... See more keywords