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Aspirin Rescues Wnt-Driven Stem-like Phenotype in Human Intestinal Organoids and Increases the Wnt Antagonist Dickkopf-1

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Published in 2020 at "Cellular and Molecular Gastroenterology and Hepatology"

DOI: 10.1016/j.jcmgh.2020.09.010

Abstract: Background & Aims Aspirin reduces colorectal cancer (CRC) incidence and mortality. Understanding the biology responsible for this protective effect is key to developing biomarker-led approaches for rational clinical use. Wnt signaling drives CRC development from… read more here.

Keywords: cell; aspirin; wnt driven; stem like ... See more keywords