NanoBiT- and NanoBiT/BRET-based assays allow the analysis of binding kinetics of WNT-3A to endogenous Frizzled 7 in a colorectal cancer model.
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DOI: 10.1111/bph.16090
Abstract: BACKGROUND AND PURPOSE WNT binding to Frizzleds (FZD) is a crucial step that leads to the initiation of signalling cascades governing multiple processes during embryonic development, stem cell regulation, and adult tissue homeostasis. Recent efforts… read more here.
Keywords: fzd7; wnt endogenous; pharmacology; colorectal cancer ... See more keywords