Discovery of novel frizzled-7 inhibitors by targeting the receptor’s transmembrane domain
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DOI: 10.18632/oncotarget.20665
Abstract: Frizzled (Fzd) proteins are seven transmembrane receptors that belong to a novel and separated family of G-protein-coupled receptors (GPCRs). The Fzd receptors can respond to Wnt proteins to activate the canonical β-catenin pathway which is… read more here.
Keywords: cancer; fzd7; transmembrane domain; wnt fzd7 ... See more keywords