Articles with "wnt gsk" as a keyword



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EPRS/GluRS promotes gastric cancer development via WNT/GSK-3β/β-catenin signaling pathway

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Published in 2021 at "Gastric Cancer"

DOI: 10.1007/s10120-021-01180-x

Abstract: Glutamyl-prolyl-tRNA synthetase (EPRS/GluRS) is primarily part of the multi-synthetase complex that may play a key role in cancer development. However, the biological function, molecular mechanism, and inhibitor of EPRS have not been investigated in gastric… read more here.

Keywords: gastric cancer; wnt gsk; gsk catenin; cancer ... See more keywords
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Daphnetin ameliorates glucocorticoid-induced osteoporosis via activation of Wnt/GSK-3β/β-catenin signaling.

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Published in 2020 at "Toxicology and applied pharmacology"

DOI: 10.1016/j.taap.2020.115333

Abstract: Glucocorticoids have been widely used in multiple inflammatory and autoimmune diseases. However, long-term glucocorticoid therapy may result in osteoporosis. The present study aimed to evaluate the potential therapeutic effects and investigate the underlying mechanisms of… read more here.

Keywords: wnt; catenin signaling; wnt gsk; daph ... See more keywords