Glypican‐4 regulated actin cytoskeletal reorganization in glucocorticoid treated trabecular meshwork cells and involvement of Wnt/PCP signaling
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.30953
Abstract: A common adverse response to the clinical use of glucocorticoids (GCs) is elevated intraocular pressure (IOP) which is a major risk factor for glaucoma. Elevated IOP arises due to impaired outflow of aqueous humor (AH)… read more here.
Keywords: wnt pcp; pcp signaling; pcp; trabecular meshwork ... See more keywords
The preventive effects of taurine on neural tube defects through the Wnt/PCP-Jnk-dependent pathway
Sign Up to like & getrecommendations! Published in 2017 at "Amino Acids"
DOI: 10.1007/s00726-017-2462-x
Abstract: The aim of this study was to clarify the protective role of taurine in neuronal apoptosis and the role of the Wnt/PCP-Jnk pathway in mediating the preventive effects of taurine on neural tube defects (NTDs).… read more here.
Keywords: jnk; pcp jnk; group; wnt pcp ... See more keywords
Highly Purified Eicosapentaenoic Acid Alleviates the Inflammatory Response and Oxidative Stress in Macrophages during Atherosclerosis via the miR-1a-3p/sFRP1/Wnt/PCP-JNK Pathway
Sign Up to like & getrecommendations! Published in 2022 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2022/9451058
Abstract: Highly purified eicosapentaenoic acid (EPA) has shown great effects in the prevention of atherosclerosis. In a murine model, it significantly reduced plaque accumulation, lowered plasma lipid levels, and decreased inflammation levels, which was also observed… read more here.
Keywords: mir; wnt pcp; wnt; pcp jnk ... See more keywords
Vangl as a Master Scaffold for Wnt/Planar Cell Polarity Signaling in Development and Disease
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.887100
Abstract: The establishment of polarity within tissues and dynamic cellular morphogenetic events are features common to both developing and adult tissues, and breakdown of these programs is associated with diverse human diseases. Wnt/Planar cell polarity (Wnt/PCP)… read more here.
Keywords: wnt pcp; wnt planar; cell; polarity ... See more keywords
CTHRC1 overexpression promotes cervical carcinoma progression by activating the Wnt/PCP signaling pathway
Sign Up to like & getrecommendations! Published in 2019 at "Oncology Reports"
DOI: 10.3892/or.2019.6963
Abstract: The tumorigenesis and metastasis of tumors are associated with human collagen triple helix repeats containing 1 (CTHRC1). To study the effects and possible impacting mechanisms of CTHRC1 on human cervical carcinoma development, samples of paraffin-embedded… read more here.
Keywords: carcinoma; cthrc1; wnt pcp; cervical carcinoma ... See more keywords