Runx2 regulates cranial suture closure by inducing hedgehog, Fgf, Wnt and Pthlh signaling pathway gene expressions in suture mesenchymal cells
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DOI: 10.1093/hmg/ddy386
Abstract: Cleidocranial dysplasia (CCD, #119600), which is characterized by hypoplastic clavicles, open fontanelles, supernumerary teeth and a short stature, is caused by heterozygous mutations in RUNX2. However, it currently remains unclear why suture closure is severely… read more here.
Keywords: pthlh signaling; fgf wnt; suture; wnt pthlh ... See more keywords