Wnt target enhancer regulation by a CDX/TCF transcription factor collective and a novel DNA motif
Sign Up to like & getrecommendations! Published in 2021 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkab657
Abstract: Abstract Transcriptional regulation by Wnt signalling is primarily thought to be accomplished by a complex of β-catenin and TCF family transcription factors (TFs). Although numerous studies have suggested that additional TFs play roles in regulating… read more here.
Keywords: tcf; cdx; wnt target; regulation ... See more keywords
USP47 deubiquitylates Groucho/TLE to promote Wnt–β-catenin signaling
Sign Up to like & getrecommendations! Published in 2023 at "Science Signaling"
DOI: 10.1126/scisignal.abn8372
Abstract: The Wnt–β-catenin signal transduction pathway is essential for embryonic development and adult tissue homeostasis. Wnt signaling converts TCF from a transcriptional repressor to an activator in a process facilitated by the E3 ligase XIAP. XIAP-mediated… read more here.
Keywords: xiap; wnt catenin; wnt; wnt signaling ... See more keywords