Wnt1 Boosts Fracture Healing by Enhancing Bone Formation in the Fracture Callus
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Bone and Mineral Research"
DOI: 10.1002/jbmr.4797
Abstract: Despite considerable improvement in fracture care, 5%–10% of all fractures still heal poorly or result in nonunion formation. Therefore, there is an urgent need to identify new molecules that can be used to improve bone… read more here.
Keywords: fracture callus; fracture; bone; wnt1 ... See more keywords
Long non-coding RNA MALAT1 sponges microRNA-429 to regulate apoptosis of hippocampal neurons in hypoxic-ischemic brain damage by regulating WNT1
Sign Up to like & getrecommendations! Published in 2019 at "Brain Research Bulletin"
DOI: 10.1016/j.brainresbull.2019.06.004
Abstract: Hypoxic-ischemic brain damage (HIBD) is a common neurological disorder. Emerging reports reveal that long non-coding RNAs and microRNAs (miRs) are implicated in the progress of HIBD. In this study we tried to ascertain whether lncRNA… read more here.
Keywords: apoptosis; mir 429; hibd; malat1 ... See more keywords
Long noncoding RNA DLGAP1-AS2 facilitates Wnt1 transcription through physically interacting with Six3 and drives the malignancy of gastric cancer
Sign Up to like & getrecommendations! Published in 2021 at "Cell Death Discovery"
DOI: 10.1038/s41420-021-00649-z
Abstract: The long noncoding RNA (lncRNA) DLGAP1-AS2 has recently been characterized as an oncogenic lncRNA in several cancers. However, its biological roles and clinical significance in gastric cancer (GC) remains barely understood. In this study, we… read more here.
Keywords: catenin signaling; wnt1; dlgap1; dlgap1 as2 ... See more keywords
Wnt1 silences chemokine genes in dendritic cells and induces adaptive immune resistance in lung adenocarcinoma
Sign Up to like & getrecommendations! Published in 2019 at "Nature Communications"
DOI: 10.1038/s41467-019-09370-z
Abstract: Lung adenocarcinoma (LUAD)-derived Wnts increase cancer cell proliferative/stemness potential, but whether they impact the immune microenvironment is unknown. Here we show that LUAD cells use paracrine Wnt1 signaling to induce immune resistance. In TCGA, Wnt1… read more here.
Keywords: lung adenocarcinoma; dendritic cells; immune resistance; wnt1 ... See more keywords
Novel mutation G324C in WNT1 mapped in a large Pakistani family with severe recessively inherited Osteogenesis Imperfecta
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Biomedical Science"
DOI: 10.1186/s12929-018-0481-x
Abstract: IntroductionOsteogenesis imperfecta (OI) is a clinically and genetically heterogeneous disease with skeletal fragility and variable extra-skeletal manifestations. To date several point mutations in 18 different genes causing different types of OI have been identified. Mutations… read more here.
Keywords: mutation g324c; imperfecta; novel mutation; family ... See more keywords
Circle RNA FOXP1 promotes cell proliferation in lung cancer by regulating miR-185-5p/Wnt1 signaling pathway.
Sign Up to like & getrecommendations! Published in 2020 at "European review for medical and pharmacological sciences"
DOI: 10.26355/eurrev_202006_21665
Abstract: OBJECTIVE It is reported that circular RNA plays an important role in various cancers in recent years. However, there is less investigation reported in lung adenocarcinoma (LUAD) about circRNA. This study aims to explore the… read more here.
Keywords: luad cell; mir 185; cell proliferation; cell ... See more keywords
GV20 Penetrating GB7 on the Expression of Wnt1 in Brain Tissue of Rats with Intracerebral Hemorrhage
Sign Up to like & getrecommendations! Published in 2017 at "Medicinal Chemistry"
DOI: 10.4172/2161-0444.10485
Abstract: Background: Intracerebral hemorrhage (ICH) is a life-threatening disease that confuses us for centuries. Acupuncture as a kind of Chinese traditional treatment has been empirically established and widely used in clinics in China, especially for stroke… read more here.
Keywords: gv20 penetrating; penetrating gb7; treatment; expression ... See more keywords