Articles with "wnt10a" as a keyword



Epithelial Wnt10a Is Essential for Tooth Root Furcation Morphogenesis

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Published in 2020 at "Journal of Dental Research"

DOI: 10.1177/0022034519897607

Abstract: WNT10A (Wingless-type MMTV integration site family, member 10A) plays a crucial role in tooth development, and patients with biallelic WNT10A mutation and mice lacking Wnt10a show taurodontism. However, whether epithelial or mesenchymal WNT10A controls the… read more here.

Keywords: cre wnt10aflox; wnt10a; root furcation; wnt10aflox flox ... See more keywords
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MiRNA-148a inhibits cell growth and drug resistance by regulating WNT10a expression in renal cell carcinoma

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Published in 2022 at "Translational Andrology and Urology"

DOI: 10.21037/tau-22-464

Abstract: Background We aimed to explore miR-148a exerts a tumor suppressor effect and arsenic trioxide (As2O3) sensitivity on renal cell carcinoma (RCC). Methods We performed polymerase chain reaction (PCR) on 42 pairs of tumor and paracancerous… read more here.

Keywords: cell; renal cell; mir 148a; expression ... See more keywords
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Diffuse Large B-Cell Lymphoma Promotes Endothelial-to-Mesenchymal Transition via WNT10A/Beta-Catenin/Snail Signaling

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Published in 2022 at "Frontiers in Oncology"

DOI: 10.3389/fonc.2022.871788

Abstract: Diffuse large B-cell lymphoma (DLBCL) is one type of highly heterogeneous lymphoid malignancy with 30%~40% of patients experiencing treatment failure. Novel risk stratification and therapeutic approaches for DLBCL are urgently needed. Endothelial-to-mesenchymal transition (EndMT), which… read more here.

Keywords: endmt; snail; catenin snail; wnt10a ... See more keywords

Deletion of Wnt10a Is Implicated in Hippocampal Neurodegeneration in Mice

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Published in 2022 at "Biomedicines"

DOI: 10.3390/biomedicines10071500

Abstract: The hippocampus plays an important role in maintaining normal cognitive function and is closely associated with the neuropathogenesis of dementia. Wnt signaling is relevant to neuronal development and maturation, synaptic formation, and plasticity. The role… read more here.

Keywords: wnt10a mice; deletion wnt10a; wnt10a; mice ... See more keywords