Secreted frizzled-related protein 5 promotes angiogenesis of human umbilical vein endothelial cells and alleviates myocardial injury in diabetic mice with myocardial infarction by inhibiting Wnt5a/JNK signaling
Sign Up to like & getrecommendations! Published in 2022 at "Bioengineered"
DOI: 10.1080/21655979.2022.2070964
Abstract: ABSTRACT The purpose of this study is to investigate whether secreted frizzled-related protein 5 (SFRP5) affects the proliferation, migration and angiogenesis of human umbilical vein endothelial cells (HUVECs) induced by high glucose (HG). HUVECs were… read more here.
Keywords: wnt5a jnk; sfrp5; jnk; mice ... See more keywords
Secreted frizzled-related protein 5 (SFRP5) protects ATDC5 cells against LPS-induced inflammation and apoptosis via inhibiting Wnt5a/JNK pathway
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Orthopaedic Surgery and Research"
DOI: 10.1186/s13018-021-02260-5
Abstract: Secreted frizzled-related protein 5 (SFRP5) is an endogenous inhibitor of Wnt5a (wingless-type family member 5a), which has been implicated in anti-inflammatory response. In this study, we aimed to investigate whether SFRP5 could protect chondrocytes against… read more here.
Keywords: sfrp5; wnt5a jnk; inflammation apoptosis; overexpression ... See more keywords