Identification of clinical candidates against West Nile virus by activity screening in vitro and effect evaluation in vivo
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Medical Virology"
DOI: 10.1002/jmv.27891
Abstract: The West Nile virus (WNV) is a member of the flavivirus and is known to cause encephalitis. There is currently no specific treatment for WNV infection. Repurposing of clinically approved drugs appeared promising for rapidly… read more here.
Keywords: wnv infection; nile virus; west nile; activity ... See more keywords
Evaluation of the protective ability of plasma from Japanese individuals against mosquito-borne viral infections
Sign Up to like & getrecommendations! Published in 2017 at "Transactions of The Royal Society of Tropical Medicine and Hygiene"
DOI: 10.1093/trstmh/trx071
Abstract: Background Most of the Japanese population is seropositive for anti-Japanese encephalitis virus (JEV) antibodies because of previous JEV vaccination or natural infection. Because the virological characteristics of JEV are similar to those of West Nile… read more here.
Keywords: japanese individuals; neutralizing activity; denv; infection ... See more keywords
Depletion of Microglia in an Ex Vivo Brain Slice Culture Model of West Nile Virus Infection Leads to Increased Viral Titers and Cell Death
Sign Up to like & getrecommendations! Published in 2022 at "Microbiology Spectrum"
DOI: 10.1128/spectrum.00685-22
Abstract: WNV infections of the CNS are rare but can have devastating long-term effects. There are currently no vaccines or specific antiviral treatments, so a better understanding of the pathogenesis and immune response to this virus… read more here.
Keywords: wnv; infection; wnv infection; increased viral ... See more keywords