Thio-Modification of tRNA at the Wobble Position as Regulator of the Kinetics of Decoding and Translocation on the Ribosome.
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DOI: 10.1021/jacs.7b00727
Abstract: Uridine 34 (U34) at the wobble position of the tRNA anticodon is post-transcriptionally modified, usually to mcm5s2, mcm5, or mnm5. The lack of the mcm5 or s2 modification at U34 of tRNALys, tRNAGlu, and tRNAGln… read more here.
Keywords: trnalys; translocation; wobble position; ribosome ... See more keywords
Inosine RNA modifications are enriched at the codon wobble position in mouse oocytes and eggs†
Sign Up to like & getrecommendations! Published in 2019 at "Biology of Reproduction"
DOI: 10.1093/biolre/ioz130
Abstract: Abstract Mammalian oocytes and eggs are transcriptionally quiescent and depend on post-transcriptional mechanisms for proper maturation. Post-transcriptional mRNA modifications comprise an important regulatory mechanism that can alter protein and miRNA recognition sites, splicing, stability, secondary… read more here.
Keywords: inosine; oocytes eggs; enriched codon; wobble position ... See more keywords