Construction of Wogonin Nanoparticle‐Containing Strontium‐Doped Nanoporous Structure on Titanium Surface to Promote Osteoporosis Fracture Repair
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202201405
Abstract: M2 polarization of macrophage is an important immunomodulatory event that attenuates inflammation. To regulate the immune microenvironment in osteoporotic conditions for enhancing bone healing, strontium‐doped nano‐structure is fabricated on the surface of titanium implant via… read more here.
Keywords: mao lblwnp; wogonin; titanium; strontium doped ... See more keywords
Simultaneous separation of glycyrrhizic acid, baicalein and wogonin from Radix Glycyrrhizae and Radix Scutellariae using foam fractionation and in vitro activity evaluation.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the science of food and agriculture"
DOI: 10.1002/jsfa.11872
Abstract: BACKGROUND In this study, the optimal conditions for the extraction and purification of glycyrrhizic acid from Radix Glycyrrhizae (RG) and baicalein and wogonin from Radix Scutellariae (RS) by foam fractionation were studied on the basis… read more here.
Keywords: radix; foam fractionation; glycyrrhizic acid; wogonin ... See more keywords
Wogonin regulates colonocyte metabolism via PPARγ to inhibit Enterobacteriaceae against dextran sulfate sodium‐induced colitis in mice
Sign Up to like & getrecommendations! Published in 2022 at "Phytotherapy Research"
DOI: 10.1002/ptr.7677
Abstract: To investigate the potential effects and mechanism of wogonin on dextran sulfate sodium (DSS)‐induced colitis, 70 male mice were administered wogonin (12.5, 25, 50 mg·kg−1·d−1, i.g.) for 10 days, meanwhile, in order to induce colitis, the mice… read more here.
Keywords: induced colitis; dss; colitis mice; wogonin ... See more keywords
Anti‐ulcerative effects of wogonin on ulcerative colitis induced by dextran sulfate sodium via Nrf2/TLR4/NF‐κB signaling pathway in BALB/c mice
Sign Up to like & getrecommendations! Published in 2022 at "Environmental Toxicology"
DOI: 10.1002/tox.23457
Abstract: Ulcerative colitis (UC) is an inflammatory disease on the deepest lining of the colon and rectum. Wogonin is an antitumor flavonoid, which possesses various therapeutic properties. Even if the anti‐colitis effect of wogonin was documented… read more here.
Keywords: colon; wogonin; signaling pathway; dextran sulfate ... See more keywords
Wogonin, a plant derived small molecule, exerts potent anti‐inflammatory and chondroprotective effects through the activation of ROS/ERK/Nrf2 signaling pathways in human Osteoarthritis chondrocytes
Sign Up to like & getrecommendations! Published in 2017 at "Free Radical Biology and Medicine"
DOI: 10.1016/j.freeradbiomed.2017.02.041
Abstract: Abstract Osteoarthritis (OA), characterized by progressive destruction of articular cartilage, is the most common form of human arthritis. Here, we evaluated the potential chondroprotective and anti‐inflammatory effects of Wogonin, a naturally occurring flavonoid, in IL‐1&bgr;‐stimulated… read more here.
Keywords: wogonin; anti inflammatory; ros erk; expression ... See more keywords
Wogonin attenuates inflammation by activating PPAR‐&ggr; in alcoholic liver disease
Sign Up to like & getrecommendations! Published in 2017 at "International Immunopharmacology"
DOI: 10.1016/j.intimp.2017.06.013
Abstract: Abstract Alcoholic liver disease (ALD) is one of the predominant causes of liver‐related morbidity and mortality worldwide. However, effective therapy for ALD is still lacking. Wogonin, a major flavonoid compound, is found in Scutellaria baicalensis… read more here.
Keywords: ppar; wogonin; alcoholic liver; ppar ggr ... See more keywords
Anti-tumor activity of wogonin, an extract from Scutellaria baicalensis, through regulating different signaling pathways.
Sign Up to like & getrecommendations! Published in 2017 at "Chinese journal of natural medicines"
DOI: 10.1016/s1875-5364(17)30005-5
Abstract: Wogonin is a plant flavonoid compound extracted from Scutellaria baicalensis (Huang-Qin or Chinese skullcap) and has been studied thoroughly by many researchers till date for its anti-viral, anti-oxidant, anti-cancerous and neuro-protective properties. Numerous experiments conducted… read more here.
Keywords: wogonin; signaling pathways; scutellaria baicalensis; anti tumor ... See more keywords
Wogonin Alleviates Cisplatin-induced Cardiotoxicity in Mice Via Inhibiting Gasdermin D-mediated Pyroptosis
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Cardiovascular Pharmacology"
DOI: 10.1097/fjc.0000000000001085
Abstract: Abstract: Cardiotoxicity has been well documented as a side effect of cisplatin (CDDP) treatment. The inflammatory response plays a crucial role in the pathological process of CDDP-induced cardiotoxicity. Wogonin is a natural flavonoid compound that… read more here.
Keywords: wogonin; pyroptosis; induced cardiotoxicity; cddp induced ... See more keywords
Wogonin attenuates the pathogenicity of Streptococcus pneumoniae by double‐target inhibition of Pneumolysin and Sortase A
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.17684
Abstract: Streptococcus pneumoniae (S. pneumoniae) is a major causative agent of respiratory disease in patients and can cause respiratory distress and other symptoms in severe cases. Pneumolysin (PLY) is a pore‐forming toxin that induces host tissue… read more here.
Keywords: pneumoniae; pathogenicity; wogonin; wogonin attenuates ... See more keywords
Wogonin, a Bioactive Ingredient from Huangqi Guizhi Formula, Alleviates Discogenic Low Back Pain via Suppressing the Overexpressed NGF in Intervertebral Discs
Sign Up to like & getrecommendations! Published in 2023 at "Mediators of Inflammation"
DOI: 10.1155/2023/4436587
Abstract: Purpose To investigate whether wogonin, a key bioactive ingredient of Huangqi Guizhi formula (HQGZ formula; a Traditional Chinese Medicine herbal formula) according to network pharmacology analysis, has analgesic effects on discogenic low back pain (LBP)… read more here.
Keywords: pharmacology; bioactive ingredient; formula; wogonin ... See more keywords
Wogonin Alleviates Kidney Tubular Epithelial Injury in Diabetic Nephropathy by Inhibiting PI3K/Akt/NF-κB Signaling Pathways
Sign Up to like & getrecommendations! Published in 2021 at "Drug Design, Development and Therapy"
DOI: 10.2147/dddt.s310882
Abstract: Introduction Kidney tubular epithelial injury is one of the key factors in the progression of diabetic nephropathy (DN). Wogonin is a kind of flavonoid, which has many pharmacological effects, such as anti-inflammation, anti-oxidation and anti-fibrosis.… read more here.
Keywords: tubular epithelial; epithelial injury; pi3k akt; wogonin ... See more keywords