Acidification of endothelial Weibel-Palade bodies is mediated by the vacuolar-type H+-ATPase
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DOI: 10.1371/journal.pone.0270299
Abstract: Weibel-Palade bodies (WPB) are unique secretory granules of endothelial cells that store the procoagulant von-Willebrand factor (VWF) in a highly compacted form. Upon exocytosis the densely packed VWF unfurls into long strands that expose binding… read more here.
Keywords: vacuolar type; type atpase; wpb; acidification ... See more keywords
Quantitative analysis of Weibel-Palade bodies
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DOI: 10.1371/journal.pone.0278044
Abstract: Weibel Palade bodies (WPBs) are vesicles found in endothelial cells which carry the multimeric protein von Willebrand factor (VWF). As cellular confluency has been shown to influence the number of WPBs in endothelial cells, we… read more here.
Keywords: palade bodies; wpb; weibel palade; wpb nuclei ... See more keywords
Weibel-Palade bodies – secretory organelles at the interface of inflammation and hemostasis
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DOI: 10.3389/fcell.2025.1624487
Abstract: Weibel-Palade bodies (WPB) are lysosome-related, secretory organelles unique to vascular endothelial cells. They serve as storage organelles for the pro-thrombotic and hemostatic glycoprotein von-Willebrand factor (VWF) as well as numerous other proteins involved in regulating… read more here.
Keywords: palade bodies; weibel palade; wpb; secretory organelles ... See more keywords