Lysophosphatidylcholine in phospholipase A2-modified LDL triggers secretion of angiopoietin 2.
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DOI: 10.1016/j.atherosclerosis.2021.04.007
Abstract: BACKGROUND AND AIMS Secretory phospholipase A2 (PLA2) hydrolyzes LDL phospholipids generating modified LDL particles (PLA2-LDL) with increased atherogenic properties. Exocytosis of Weibel-Palade bodies (WPB) releases angiopoietin 2 (Ang2) and externalizes P-selectin, which both play important… read more here.
Keywords: pla2 ldl; modified ldl; pla2; wpb exocytosis ... See more keywords