Dissecting the Kinetic Mechanism of Human Lysine Methyltransferase 2D and Its Interactions with the WRAD2 Complex
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DOI: 10.1021/acs.biochem.2c00385
Abstract: Human lysine methyltransferase 2D (hKMT2D) is an epigenetic writer catalyzing the methylation of histone 3 lysine 4. hKMT2D by itself has little catalytic activity and reaches full activation as part of the WRAD2 complex, additionally… read more here.
Keywords: set domain; wrad2 complex; human lysine; mechanism ... See more keywords