Readers, writers and erasers of N6-methylated adenosine modification.
Sign Up to like & getrecommendations! Published in 2017 at "Current opinion in structural biology"
DOI: 10.1016/j.sbi.2017.05.011
Abstract: N6-methyladenosine (m6A) as the most prevalent internal modification in mammalian RNAs has been increasingly realized as an important reversible mark that participates in various biological processes and cancer pathogenesis. In this review, we discuss the… read more here.
Keywords: writers erasers; erasers methylated; readers writers; domain family ... See more keywords
RM2Target: a comprehensive database for targets of writers, erasers and readers of RNA modifications
Sign Up to like & getrecommendations! Published in 2022 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkac945
Abstract: Abstract RNA modification is a dynamic and reversible process regulated by a series of writers, erasers and readers (WERs). Abnormal changes of WERs will disrupt the RNA modification homeostasis of their target genes, leading to… read more here.
Keywords: erasers readers; writers erasers; rna modification; database ... See more keywords
Effects of writers, erasers and readers within miRNA‐related m6A modification in cancers
Sign Up to like & getrecommendations! Published in 2022 at "Cell Proliferation"
DOI: 10.1111/cpr.13340
Abstract: As one of the most abundant post‐transcriptional mRNA modifications, N6‐methyladenosine (m6A) has attracted extensive attention from scientists. Emerging evidence indicates that m6A modification plays a significant role in cancer‐related signalling pathways. Existing research demonstrates that… read more here.
Keywords: erasers readers; modification; writers erasers; m6a modification ... See more keywords