P2254Impaired autophagic off-rate causes cardiac aging in progeria mouse model
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DOI: 10.1093/eurheartj/ehz748.0732
Abstract: Aging is known to be one of the primary causes of heart failure. Werner syndrome is one of the aging disorder that caused by dysfunction of DNA helicase-regulatory protein (WRN). However, there is little information… read more here.
Keywords: wrn; heart; cardiac aging; wrn k577m ... See more keywords