WT1 gene: a potential therapeutic target for multiple cancer treatment strategies
Sign Up to like & getrecommendations! Published in 2025 at "Clinical and Experimental Medicine"
DOI: 10.1007/s10238-025-01769-x
Abstract: The Wilms’ Tumor 1 (WT1) gene has attracted significant attention in oncological research owing to its involvement in the pathogenesis of a variety of malignancies. Initially identified in association with Wilms’ tumor, a pediatric renal… read more here.
Keywords: treatment strategies; cancer; wt1 gene; potential therapeutic ... See more keywords
OC8 High prevalence of wt1 gene mutations in patients with steroid-resistant nephrotic syndrome
Sign Up to like & getrecommendations! Published in 2019 at "Archives of Disease in Childhood"
DOI: 10.1136/archdischild-2019-epa.8
Abstract: Background and aims Steroid-resistant nephrotic syndrome (SRNS) is the rare disease and holds a special place in structure of nephrotic syndrome in children, it takes up to 15–25% among other forms of the nephrotic syndrome.… read more here.
Keywords: resistant nephrotic; steroid resistant; wt1 gene; gene ... See more keywords
Heterogeneity of human WT1 gene.
Sign Up to like & getrecommendations! Published in 2017 at "Postepy higieny i medycyny doswiadczalnej"
DOI: 10.5604/01.3001.0010.3840
Abstract: The WT1 gene, characterized by an extremely complex structure, is located on chromosome 11. It is involved in cell growth and differentiation, and has a strong impact on consecutive stages of the functioning of the… read more here.
Keywords: gene; wt1 gene; heterogeneity human; human wt1 ... See more keywords