Prognostic impact of peripheral blood WT1-mRNA expression in patients with MDS
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DOI: 10.1038/s41408-019-0248-y
Abstract: Few reports suggested a prognostic impact of Wilms‘ Tumor-1 (WT1)-mRNA overexpression in MDS, but translation into clinical routine was hampered by limited patients numbers, differing sample sources, non-standardized methods/cut-offs. To evaluate whether WT1-mRNA expression yields… read more here.
Keywords: wt1 mrna; prognostic impact; mrna expression; wt1 ... See more keywords
Dynamic Change of Peripheral Blood WT1-mRNA within Three Cycles of Azacitidine Therapy Predicts Treatment Response in High-Risk Myelodysplastic Syndrome
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DOI: 10.1182/blood-2020-138377
Abstract: Introduction. Hypomethylating agents azacitidine (AZA) and decitabine are standard of care for myelodysplastic syndromes (MDS). Considering the result of the secondary analysis of the AZA-001 trial showing 91% of first responses occurred within 6 cycles,… read more here.
Keywords: wt1 mrna; response; three cycles; cycles aza ... See more keywords