WTAP facilitates progression of endometrial cancer via CAV‐1/NF‐κB axis
Sign Up to like & getrecommendations! Published in 2021 at "Cell Biology International"
DOI: 10.1002/cbin.11570
Abstract: The N6‐methyladenosine (m6A) modification is one of the most prevalent methylations in eukaryotic messenger RNA (mRNA), and it is essential for the development of many important biological processes such as multiple types of tumors. One… read more here.
Keywords: facilitates progression; wtap facilitates; endometrial cancer; wtap ... See more keywords
WTAP contributes to the tumorigenesis of osteosarcoma via modulating ALB in an m6A‐dependent manner
Sign Up to like & getrecommendations! Published in 2023 at "Environmental Toxicology"
DOI: 10.1002/tox.23780
Abstract: Osteosarcoma (OS) is a prevalent bone malignancy mainly occurred in adolescents. WTAP/N6‐methyladenosine (m6A) modification is confirmed to be involved in OS progression. This study is conducted to bring some novel insights to the action mechanism… read more here.
Keywords: wtap; contributes tumorigenesis; wtap contributes; tumorigenesis osteosarcoma ... See more keywords
WTAP-Mediated m6A RNA Methylation Regulates the Differentiation of Bone Marrow Mesenchymal Stem Cells via the miR-29b-3p/HDAC4 Axis
Sign Up to like & getrecommendations! Published in 2023 at "Stem Cells Translational Medicine"
DOI: 10.1093/stcltm/szad020
Abstract: Abstract N6-methyladenosine (m6A) methylation, a well-known modification with new epigenetic functions, has been reported to participate in the progression of osteoporosis (OP), providing novel insights into the pathogenesis of OP. However, as the key component… read more here.
Keywords: mir 29b; wtap; methylation; wtap mediated ... See more keywords
Comprehensive analysis about prognostic and immunological role of WTAP in pan-cancer
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.1007696
Abstract: Background: Wilms tumor 1-associated protein (WTAP) plays a critical role in ribonucleic acid (RNA) methylation of N6 adenosine (m6A) modification, which is closely related with varieties of biological process. However, the role of WTAP in… read more here.
Keywords: wtap; role wtap; pan cancer; expression ... See more keywords
Role of WTAP in Cancer: From Mechanisms to the Therapeutic Potential
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DOI: 10.3390/biom12091224
Abstract: Wilms’ tumor 1-associating protein (WTAP) is required for N6-methyladenosine (m6A) RNA methylation modifications, which regulate biological processes such as RNA splicing, cell proliferation, cell cycle, and embryonic development. m6A is the predominant form of mRNA… read more here.
Keywords: wtap; role; role wtap; cancer mechanisms ... See more keywords