Van Wyk-Grumbach syndrome: A rare cause of precocious puberty.
Sign Up to like & getrecommendations! Published in 2018 at "Presse medicale"
DOI: 10.1016/j.lpm.2018.02.012
Abstract: Introduction Profound primary hypothyroidism in children causes generally delayed pubertal development. Rare association with precocious puberty may occur especially in long standing untreated patients. The cardinal features of hypothyroidism inducing isosexual precocious puberty include thelarche,… read more here.
Keywords: puberty; van wyk; precocious puberty; wyk grumbach ... See more keywords
Van Wyk Grumbach Syndrome and Ovarian Hyperstimulation in Juvenile Primary Hypothyroidism: Lessons From a 30-Case Cohort
Sign Up to like & getrecommendations! Published in 2023 at "Journal of the Endocrine Society"
DOI: 10.1210/jendso/bvad042
Abstract: Abstract Context Prolonged hypothyroidism in children commonly causes short stature with delayed bone maturation, and delayed puberty. However, a paradoxical occurrence of peripheral precocious puberty and pituitary enlargement in chronically untreated juvenile hypothyroidism was first… read more here.
Keywords: hypothyroidism; wyk grumbach; van wyk; grumbach syndrome ... See more keywords
Van Wyk Grumbach Syndrome.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of the College of Physicians and Surgeons--Pakistan : JCPSP"
DOI: 10.29271/jcpsp.2020.12.1332
Abstract: Van Wyk Grumbach syndrome is well known for protracted hypothyroidism, characterised by multicystic ovaries (normal size ovaries contain many follicles of various sizes), isosexual precocious puberty and delayed skeletal growth. A series of ten children… read more here.
Keywords: wyk grumbach; grumbach syndrome; van wyk;