WZ3146 inhibits mast cell Lyn and Fyn to reduce IgE-mediated allergic responses in vitro and in vivo.
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DOI: 10.1016/j.taap.2019.114763
Abstract: Mast cells (MCs) play an important role as effector cells that cause allergic responses in allergic diseases. For these reasons, MC is considered an attractive therapeutic target for allergic disease treatment. In this study, we… read more here.
Keywords: ige mediated; allergic responses; lyn fyn; mediated allergic ... See more keywords