Analysis of fouling and breakthrough of process related impurities during depth filtration using confocal microscopy
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DOI: 10.1002/btpr.3233
Abstract: Titer improvement has driven process intensification in mAb manufacture. However, this has come with the drawback of high cell densities and associated process related impurities such as cell debris, host cell protein (HCP), and DNA.… read more here.
Keywords: related impurities; x0sp; filter; microscopy ... See more keywords