XAF1 as a modifier of p53 function and cancer susceptibility
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DOI: 10.1126/sciadv.aba3231
Abstract: The XAF1-E134* variant increases the cancer risk for carriers of the TP53-R337H allele. Cancer risk is highly variable in carriers of the common TP53-R337H founder allele, possibly due to the influence of modifier genes. Whole-genome… read more here.
Keywords: xaf1 e134; xaf1 modifier; tp53 r337h; cancer ... See more keywords