Pt‐Pd Bimetallic Nanoparticles Decorated Nanoporous Graphene as a Catalytic Amplification Platform for Electrochemical Detection of Xanthine
Sign Up to like & getrecommendations! Published in 2017 at "Electroanalysis"
DOI: 10.1002/elan.201600783
Abstract: The nanoporous graphene papers (NGPs) was prepared by the hard-template method. The Pt-Pd modified NGPs hybrid was prepared by the self-assembly method. Then a glassy carbon electrode (GCE) modified with Pt-Pd bimetallic nanoparticles-functionalized nanoporous graphene… read more here.
Keywords: detection; nanoporous graphene; bimetallic nanoparticles; graphene ... See more keywords
Effect of allicin and its mechanism of action in purine removal in turbot.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of food science"
DOI: 10.1111/1750-3841.15394
Abstract: Low-purine food is not only the focus of gout patients, but also the focus of contemporary green diet development. Fish are usually considered as high-purine foodstuff because of the high nutritional value and high purine… read more here.
Keywords: mechanism; xanthine; allicin; effect allicin ... See more keywords
POS1128 COMBINATION TREATMENT OF AR882, A NEW URAT1 INHIBITOR, AND XANTHINE OXIDASE INHIBITORS ALLOPURINOL OR FEBUXOSTAT: EFFECT ON URIC ACID, HYPOXANTHINE AND XANTHINE IN PLASMA OR SERUM AND URINE
Sign Up to like & getrecommendations! Published in 2021 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2021-eular.1215
Abstract: Xanthine oxidase inhibitors (XOI) are commonly used as urate lowering therapy (ULT) for the treatment of gout. Allopurinol, the first-line treatment, demonstrates low response rate (< 40%), defined as serum urate (sUA) lowering effect below… read more here.
Keywords: allopurinol febuxostat; combination; xanthine; treatment ... See more keywords
The renal phenotype of allopurinol-treated HPRT-deficient mouse
Sign Up to like & getrecommendations! Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0173512
Abstract: Excess of uric acid is mainly treated with xanthine oxidase (XO) inhibitors, also called uricostatics because they block the conversion of hypoxanthine and xanthine into urate. Normally, accumulation of upstream metabolites is prevented by the… read more here.
Keywords: hprt; xanthine; phenotype allopurinol; renal phenotype ... See more keywords
Association of Mutations Identified in Xanthinuria with the Function and Inhibition Mechanism of Xanthine Oxidoreductase
Sign Up to like & getrecommendations! Published in 2021 at "Biomedicines"
DOI: 10.3390/biomedicines9111723
Abstract: Xanthine oxidoreductase (XOR) is an enzyme that catalyzes the two-step reaction from hypoxanthine to xanthine and from xanthine to uric acid in purine metabolism. XOR generally carries dehydrogenase activity (XDH) but is converted into an… read more here.
Keywords: mechanism; xanthine; xor; function ... See more keywords
Insights into the Inhibitory Mechanism of Viniferifuran on Xanthine Oxidase by Multiple Spectroscopic Techniques and Molecular Docking
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27227730
Abstract: Viniferifuran was investigated for its potential to inhibit the activity of xanthine oxidase (XO), a key enzyme catalyzing xanthine to uric acid. An enzyme kinetics analysis showed that viniferifuran possessed a strong inhibition on XO… read more here.
Keywords: molecular docking; viniferifuran; xanthine; xanthine oxidase ... See more keywords