BRAF/MEK double blockade in refractory anaplastic pleomorphic xanthoastrocytoma
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DOI: 10.1212/wnl.0000000000003767
Abstract: A 32-year-old woman was diagnosed in February 2012 with a grade II pleomorphic xanthoastrocytoma (PXA) of the right parietal lobe. A complete excision was performed, followed by tumor bed irradiation (66 Gy). A local relapse… read more here.
Keywords: xanthoastrocytoma; braf mek; mek double; blockade refractory ... See more keywords
Identification of BRAF p. V600E-Mutant and Wild-Type by MR Imaging in Pleomorphic Xanthoastrocytoma and Anaplastic Pleomorphic Xanthoastrocytoma
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DOI: 10.3174/ajnr.a7324
Abstract: BACKGROUND AND PURPOSE: Compared with BRAF p. V600E wild-type pleomorphic xanthoastrocytoma, BRAF p. V600E-mutant pleomorphic xanthoastrocytoma showed a higher survival rate. In this study, we focused on finding preoperative MR imaging differences between BRAF p.… read more here.
Keywords: v600e mutant; pleomorphic xanthoastrocytoma; xanthoastrocytoma; anaplastic pleomorphic ... See more keywords