Antiproliferative and antioxidant activity of xanthohumol acyl derivatives
Sign Up to like & getrecommendations! Published in 2017 at "Medicinal Chemistry Research"
DOI: 10.1007/s00044-017-1887-9
Abstract: A series of mono- and diacyl- xanthohumol (1) derivatives was synthesized with yields of 10–30%. All the compounds were tested against the antiproliferative activity of human cancer cell line of colon adenocarcinoma (HT-29) using SRB… read more here.
Keywords: antioxidant activity; antioxidant capacity; xanthohumol; trolox equivalent ... See more keywords
A kinetic study of xanthohumol cyclization to isoxanthohumol – A role of water
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Molecular Structure"
DOI: 10.1016/j.molstruc.2017.03.027
Abstract: Abstract Xanthohumol, a major prenylated chalcone found in hop resin, has recently attracted scientific interest due to its health-promoting properties. In the present work, we investigated the mechanism of xanthohumol cyclization to isoxanthohumol in an… read more here.
Keywords: xanthohumol; water; cyclization; kinetic study ... See more keywords
Xanthohumol inhibits non-small cell lung cancer by activating PUMA-mediated apoptosis.
Sign Up to like & getrecommendations! Published in 2022 at "Toxicology"
DOI: 10.1016/j.tox.2022.153141
Abstract: Deregulation of apoptosis signaling is an important feature of cancer cells and plays an essential role in tumorigenesis. Xanthohumol is an active ingredient in Traditional Chinese Medicines Hops (Humulus lupulus L.). Recently studies have shown… read more here.
Keywords: cancer; puma; apoptosis; non small ... See more keywords
Analyzing bioactive effects of the minor hop compound xanthohumol C on human breast cancer cells using quantitative proteomics
Sign Up to like & getrecommendations! Published in 2019 at "PLoS ONE"
DOI: 10.1371/journal.pone.0213469
Abstract: Minor prenylated hop compounds have been attracting increasing attention due to their promising anticarcinogenic properties. Even after intensive purification from natural raw extracts, allocating certain activities to single compounds or complex interactions of the main… read more here.
Keywords: using quantitative; human breast; xanthohumol; breast cancer ... See more keywords
Xanthohumol in XERME ®, a xanthohumol‐enriched roasted malt extract, and protection of DNA from oxidative damage: evaluation of a health claim pursuant to Article 13(5) of Regulation (EC) No 1924/2006
Sign Up to like & getrecommendations! Published in 2018 at "EFSA Journal"
DOI: 10.2903/j.efsa.2018.5192
Abstract: Abstract Following an application from TA‐XAN AG, submitted for authorisation of a health claim pursuant to Article 13(5) of Regulation (EC) No 1924/2006 via the Competent Authority of Germany, the EFSA Panel on Dietetic Products,… read more here.
Keywords: claim; xanthohumol; oxidative damage; xanthohumol xerme ... See more keywords
Anti-Remodeling Effects of Xanthohumol-Fortified Beer in Pulmonary Arterial Hypertension Mediated by ERK and AKT Inhibition
Sign Up to like & getrecommendations! Published in 2019 at "Nutrients"
DOI: 10.3390/nu11030583
Abstract: Polyphenols present in some alcoholic beverages have been linked to beneficial effects in preventing cardiovascular diseases. Polyphenols found in beer with anti-proliferative and anti-cancer properties are appealing in the context of the quasi-malignant phenotype of… read more here.
Keywords: xanthohumol fortified; xanthohumol; arterial hypertension; pulmonary arterial ... See more keywords