SARS‐CoV‐2 XBB.1.16 variant: India in focus?
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Medical Virology"
DOI: 10.1002/jmv.28829
Abstract: Until February 2023, the majority of COVID‐19 cases were associated with SARS‐CoV‐2 subvariants, such as BF.7, BQ.1, BQ.1.1, and XBB.1.5, and XBB.1.9. However, the recent surge in cases has been precipitated by a novel Omicron… read more here.
Keywords: xbb; xbb variant; india; number ... See more keywords
A panel of multivalent nanobodies broadly neutralizing Omicron subvariants and recombinant
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Medical Virology"
DOI: 10.1002/jmv.29528
Abstract: The emerging Omicron subvariants have a remarkable ability to spread and escape nearly all current monoclonal antibody (mAb) treatments. Although the virulence of SARS‐CoV‐2 has now diminished, it remains a significant threat to public health… read more here.
Keywords: panel multivalent; panel; xbb; omicron ... See more keywords
Poor durability of the neutralizing response against XBB sublineages after a bivalent mRNA COVID‐19 booster dose in persons with HIV
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Medical Virology"
DOI: 10.1002/jmv.29598
Abstract: We estimated the dynamics of the neutralizing response against XBB sublineages and T cell response in persons with HIV (PWH) with previous AIDS and/or CD4 read more here.
Keywords: xbb sublineages; xbb; response; neutralizing response ... See more keywords
Effectiveness of BNT162b2 XBB vaccine in the US Veterans Affairs Healthcare System
Sign Up to like & getrecommendations! Published in 2024 at "Nature Communications"
DOI: 10.1038/s41467-024-53842-w
Abstract: Data evaluating effectiveness of XBB.1.5-adapted vaccines against JN.1-related endpoints are scarce. This nationwide test-negative case-control study within the US Veterans Affairs Healthcare System aims to estimate vaccine effectiveness (VE) of BNT162b2 XBB.1.5-adapted vaccine compared to… read more here.
Keywords: effectiveness bnt162b2; xbb; healthcare system; veterans affairs ... See more keywords
Evaluating the safety of XBB.1.5-containing COVID-19 mRNA vaccines using a self-controlled case series study
Sign Up to like & getrecommendations! Published in 2025 at "Nature Communications"
DOI: 10.1038/s41467-025-61613-4
Abstract: The safety of XBB.1.5-containing COVID-19 mRNA vaccines warrants investigation. We assessed the relative risk of 15 adverse events following the XBB.1.5 vaccination using a self-controlled case series study design with data from the National COVID… read more here.
Keywords: xbb; containing covid; xbb containing; mrna vaccines ... See more keywords
Preclinical characterization of the Omicron XBB.1.5-adapted BNT162b2 COVID-19 vaccine
Sign Up to like & getrecommendations! Published in 2024 at "NPJ Vaccines"
DOI: 10.1038/s41541-024-01013-9
Abstract: As SARS-CoV-2 evolves, increasing in potential for greater transmissibility and immune escape, updated vaccines are needed to boost adaptive immunity to protect against COVID-19 caused by circulating strains. Here, we report features of the monovalent… read more here.
Keywords: xbb adapted; xbb; omicron xbb; adapted bnt162b2 ... See more keywords
An adjuvanted chimeric spike antigen boosts lung-resident memory T-cells and induces pan-sarbecovirus protective immunity
Sign Up to like & getrecommendations! Published in 2025 at "NPJ Vaccines"
DOI: 10.1038/s41541-025-01144-7
Abstract: Next-generation vaccines are essential to address the evolving nature of SARS-CoV-2 and to protect against emerging pandemic threats from other coronaviruses. These vaccines should elicit broad protection, provide long-lasting immunity and ensure equitable access for… read more here.
Keywords: sars cov; spike; xbb; resident memory ... See more keywords
Genomic epidemiology and evolutionary analysis during XBB.1.16-predominant periods of SARS-CoV-2 omicron variant in Bangkok, Thailand: December 2022–August 2023
Sign Up to like & getrecommendations! Published in 2024 at "Scientific Reports"
DOI: 10.1038/s41598-023-50856-0
Abstract: The growing occurrence of novel recombinants, such as XBB.1.16, has emerged and become predominant, raising concerns about the impact of genomic recombination on the evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This study… read more here.
Keywords: epidemiology; sars cov; analysis; xbb ... See more keywords
Genomic surveillance and vaccine response to the dominant SARS-CoV-2 XBB lineage in Rio Grande do Sul
Sign Up to like & getrecommendations! Published in 2024 at "Scientific Reports"
DOI: 10.1038/s41598-024-67828-7
Abstract: The COVID-19 pandemic has been marked by novel viral variants, posing challenges to global public health. Recombination, a viral evolution mechanism, is implicated in SARS-CoV-2's ongoing evolution. The XBB recombinant lineage, known for evading antibody-mediated… read more here.
Keywords: sars cov; rio grande; xbb; lineage ... See more keywords
Virological characteristics of the SARS-CoV-2 XBB variant derived from recombination of two Omicron subvariants
Sign Up to like & getrecommendations! Published in 2022 at "Nature Communications"
DOI: 10.1101/2022.12.27.521986
Abstract: XBB is the first recombinant, globally dominant variant of SARS-CoV-2. Here, the authors examine the variant’s origins and virological properties, showing it is the first example of SARS-CoV-2 improving its fitness through recombination. In late… read more here.
Keywords: xbb; xbb variant; omicron subvariants; sars cov ... See more keywords
Immunogenicity and safety of a monovalent Omicron XBB.1.5 SARS-CoV-2 recombinant spike protein vaccine in previously unvaccinated, SARS-CoV-2 seropositive participants: primary day-28 analysis of a phase 2/3 open-label study
Sign Up to like & getrecommendations! Published in 2024 at "Vaccine"
DOI: 10.1101/2024.10.25.24316129
Abstract: Background Most of the population has been infected with SARS-CoV-2 and, thus, is primed by natural exposure. As such, it was assessed whether a single dose of the monovalent XBB.1.5 vaccine, NVX-CoV2601, elicited a comparable… read more here.
Keywords: sars cov; xbb; vaccine; vaccine naive ... See more keywords