IRE1α-XBP1 inhibitors exerted anti-tumor activities in Ewing’s sarcoma
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DOI: 10.18632/oncotarget.24467
Abstract: Ewing's sarcoma (ES) is the second-most frequent pediatric bone tumor. Chromosomal translocation t(11;22)(q24:q12) results in the formation of EWS/FLI1 gene fusion, which is detected in approximately 90% of tumors of the Ewing family. Several transcriptome… read more here.
Keywords: ews fli1; ire1 xbp1; tumor; xbp1 inhibitors ... See more keywords