Xbp1s-Ddit3 promotes MCT-induced pulmonary hypertension.
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DOI: 10.1042/cs20210612
Abstract: Pulmonary hypertension (PH) is a life-threatening disease characterized by vascular remodeling. Exploring new therapy target is urgent. The purpose of this study is to investigate whether and how spliced x-box binding protein 1 (xbp1s), a… read more here.
Keywords: protein; pulmonary hypertension; xbp1s; mct induced ... See more keywords
Commentary on: Xbp1s-Ddit3, DNA damage and pulmonary hypertension.
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DOI: 10.1042/cs20211095
Abstract: In this commentary, we discuss new observations stating that spliced X-box-binding protein 1 (Xbp1s)-DNA damage-inducible transcript 3 (Ddit3) promotes monocrotaline (MCT)-induced pulmonary hypertension (Jiang et al., Clinical Science (2021) 135(21), https://doi.org/10.1042/CS20210612). Xbp1s-Ddit3 is involved in… read more here.
Keywords: xbp1s ddit3; dna damage; pulmonary hypertension; damage ... See more keywords